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Page 1
Multimodal molecular imaging system for pathway-specific reporter gene expression.
Rossi M, Massai L, Diamanti D, Fiengo P, De Rosa A, Magrini R, Magnoni L, Chellini S, Coniglio S, Diodato E, Pilli E, Caradonna NP, Sardone G, Monti M, Roggeri R, Lionetti V, Recchia F, Tunici P, Valensin S, Scali C, Pollio G, Porcari V. Rossi M, et al. Among authors: caradonna np. Eur J Pharm Sci. 2016 Apr 30;86:136-42. doi: 10.1016/j.ejps.2016.03.006. Epub 2016 Mar 14. Eur J Pharm Sci. 2016. PMID: 26987608
Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors.
Pasquini S, De Rosa M, Ligresti A, Mugnaini C, Brizzi A, Caradonna NP, Cascio MG, Bolognini D, Pertwee RG, Di Marzo V, Corelli F. Pasquini S, et al. Among authors: caradonna np. Eur J Med Chem. 2012 Dec;58:30-43. doi: 10.1016/j.ejmech.2012.09.035. Epub 2012 Oct 3. Eur J Med Chem. 2012. PMID: 23085772
siRNA screen identifies QPCT as a druggable target for Huntington's disease.
Jimenez-Sanchez M, Lam W, Hannus M, Sönnichsen B, Imarisio S, Fleming A, Tarditi A, Menzies F, Dami TE, Xu C, Gonzalez-Couto E, Lazzeroni G, Heitz F, Diamanti D, Massai L, Satagopam VP, Marconi G, Caramelli C, Nencini A, Andreini M, Sardone GL, Caradonna NP, Porcari V, Scali C, Schneider R, Pollio G, O'Kane CJ, Caricasole A, Rubinsztein DC. Jimenez-Sanchez M, et al. Among authors: caradonna np. Nat Chem Biol. 2015 May;11(5):347-354. doi: 10.1038/nchembio.1790. Epub 2015 Apr 6. Nat Chem Biol. 2015. PMID: 25848931 Free PMC article.
Structure-activity relationship and properties optimization of a series of quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway.
Nencini A, Pratelli C, Quinn JM, Salerno M, Tunici P, De Robertis A, Valensin S, Mennillo F, Rossi M, Bakker A, Benicchi T, Cappelli F, Turlizzi E, Nibbio M, Caradonna NP, Zanelli U, Andreini M, Magnani M, Varrone M. Nencini A, et al. Among authors: caradonna np. Eur J Med Chem. 2015 May 5;95:526-45. doi: 10.1016/j.ejmech.2015.03.055. Epub 2015 Mar 25. Eur J Med Chem. 2015. PMID: 25847770
Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.
Manetti F, Santucci A, Locatelli GA, Maga G, Spreafico A, Serchi T, Orlandini M, Bernardini G, Caradonna NP, Spallarossa A, Brullo C, Schenone S, Bruno O, Ranise A, Bondavalli F, Hoffmann O, Bologna M, Angelucci A, Botta M. Manetti F, et al. Among authors: caradonna np. J Med Chem. 2007 Nov 15;50(23):5579-88. doi: 10.1021/jm061449r. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929792