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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 1
1988 1
1989 2
1990 1
1991 3
1992 2
1993 2
1994 3
1995 1
1998 1
2003 3
2004 1
2005 1
2007 1
2009 4
2010 3
2013 1
2015 1
2016 2
2017 2
2018 3
2022 0
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38 results
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Page 1
Voltage-gated potassium channels as therapeutic targets.
Wulff H, Castle NA, Pardo LA. Wulff H, et al. Among authors: castle na. Nat Rev Drug Discov. 2009 Dec;8(12):982-1001. doi: 10.1038/nrd2983. Nat Rev Drug Discov. 2009. PMID: 19949402 Free PMC article. Review.
Aquaporins as targets for drug discovery.
Castle NA. Castle NA. Drug Discov Today. 2005 Apr 1;10(7):485-93. doi: 10.1016/S1359-6446(05)03390-8. Drug Discov Today. 2005. PMID: 15809194 Review.
Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors.
Sammons MF, Kharade SV, Filipski KJ, Boehm M, Smith AC, Shavnya A, Fernando DP, Dowling MS, Carpino PA, Castle NA, Zellmer SG, Antonio BM, Gosset JR, Carlo A, Denton JS. Sammons MF, et al. Among authors: castle na. ACS Med Chem Lett. 2018 Jan 19;9(2):125-130. doi: 10.1021/acsmedchemlett.7b00481. eCollection 2018 Feb 8. ACS Med Chem Lett. 2018. PMID: 29456800 Free PMC article.
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.
Storer RI, Pike A, Swain NA, Alexandrou AJ, Bechle BM, Blakemore DC, Brown AD, Castle NA, Corbett MS, Flanagan NJ, Fengas D, Johnson MS, Jones LH, Marron BE, Payne CE, Printzenhoff D, Rawson DJ, Rose CR, Ryckmans T, Sun J, Theile JW, Torella R, Tseng E, Warmus JS. Storer RI, et al. Among authors: castle na. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4805-4811. doi: 10.1016/j.bmcl.2017.09.056. Epub 2017 Sep 28. Bioorg Med Chem Lett. 2017. PMID: 29029933
GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.
Loucif AJC, Saintot PP, Liu J, Antonio BM, Zellmer SG, Yoger K, Veale EL, Wilbrey A, Omoto K, Cao L, Gutteridge A, Castle NA, Stevens EB, Mathie A. Loucif AJC, et al. Among authors: castle na. Br J Pharmacol. 2018 Jun;175(12):2272-2283. doi: 10.1111/bph.14098. Epub 2017 Dec 29. Br J Pharmacol. 2018. PMID: 29150838 Free PMC article.
Aryl sulfonamido tetralin inhibitors of the Kv1.5 ion channel.
Gross MF, Castle NA, Zou A, Wickenden AD, Yu W, Spear KL. Gross MF, et al. Among authors: castle na. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3063-6. doi: 10.1016/j.bmcl.2009.04.002. Epub 2009 Apr 8. Bioorg Med Chem Lett. 2009. PMID: 19398199
38 results