Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1996 2
1998 2
1999 6
2000 8
2001 14
2002 22
2003 18
2004 30
2005 41
2006 68
2007 65
2008 61
2009 88
2010 121
2011 179
2012 235
2013 281
2014 295
2015 360
2016 406
2017 454
2018 508
2019 514
2020 623
2021 662
2022 694
2023 668
2024 599

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

6,216 results

Results by year

Filters applied: . Clear all
Page 1
CD163 and inflammation: biological, diagnostic, and therapeutic aspects.
Etzerodt A, Moestrup SK. Etzerodt A, et al. Antioxid Redox Signal. 2013 Jun 10;18(17):2352-63. doi: 10.1089/ars.2012.4834. Epub 2012 Oct 19. Antioxid Redox Signal. 2013. PMID: 22900885 Free PMC article. Review.
Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. ...The biomarker form of CD163 is the soluble plasma CD163 that arises from the increased shedding of CD163 mediated by the tumor necrosis fa …
Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. ...The biomarker form …
Targeting of CD163(+) Macrophages in Inflammatory and Malignant Diseases.
Skytthe MK, Graversen JH, Moestrup SK. Skytthe MK, et al. Int J Mol Sci. 2020 Jul 31;21(15):5497. doi: 10.3390/ijms21155497. Int J Mol Sci. 2020. PMID: 32752088 Free PMC article. Review.
The phenotypes are characterized by different surface markers and the present review describes recent progress in drug-targeting of the surface marker CD163 expressed in a subpopulation of macrophages. CD163 is an abundant endocytic receptor for multiple ligands, qu …
The phenotypes are characterized by different surface markers and the present review describes recent progress in drug-targeting of the surf …
The TWEAK/Fn14/CD163 axis-implications for metabolic disease.
Ratajczak W, Atkinson SD, Kelly C. Ratajczak W, et al. Rev Endocr Metab Disord. 2022 Jun;23(3):449-462. doi: 10.1007/s11154-021-09688-4. Epub 2021 Sep 20. Rev Endocr Metab Disord. 2022. PMID: 34542797 Free PMC article. Review.
Consistent data show a role for the TWEAK/FN14/CD163 axis in metabolic disease, chronic autoimmune diseases, and acute ischaemic stroke. ...This review details the current understanding of the TWEAK/Fn14/CD163 axis as one of the chief regulators of immune signalling …
Consistent data show a role for the TWEAK/FN14/CD163 axis in metabolic disease, chronic autoimmune diseases, and acute ischaemic stro …
Identification of New Compounds against PRRSV Infection by Directly Targeting CD163.
Zhu J, He X, Bernard D, Shen J, Su Y, Wolek A, Issacs B, Mishra N, Tian X, Garmendia A, Tang Y. Zhu J, et al. J Virol. 2023 May 31;97(5):e0005423. doi: 10.1128/jvi.00054-23. Epub 2023 May 3. J Virol. 2023. PMID: 37133376 Free PMC article.
We confirmed that the highly active compounds physically bind to the CD163-SRCR5 protein, with dissociation constant (K(D)) values ranging from 28 to 39 muM. ...We also demonstrated the physical association of these compounds with the SRCR5 domain of CD163. In addit …
We confirmed that the highly active compounds physically bind to the CD163-SRCR5 protein, with dissociation constant (K(D)) values ra …
The clinical utility of CD163 in viral diseases.
Yap YJ, Wong PF, AbuBakar S, Sam SS, Shunmugarajoo A, Soh YH, Misbah S, Ab Rahman AK. Yap YJ, et al. Clin Chim Acta. 2023 Feb 15;541:117243. doi: 10.1016/j.cca.2023.117243. Epub 2023 Feb 4. Clin Chim Acta. 2023. PMID: 36740088 Review.
CD163 and other macrophage activation markers have been commonly included in the investigation of disease pathogenesis and progression. This review provides an overview of the involvement of CD163 in viral diseases. The clinical utility of CD163 in viral dise …
CD163 and other macrophage activation markers have been commonly included in the investigation of disease pathogenesis and progressio …
Alterations of CD163 expression in the complications of diabetes: A systematic review.
Siwan E, Twigg SM, Min D. Siwan E, et al. J Diabetes Complications. 2022 Apr;36(4):108150. doi: 10.1016/j.jdiacomp.2022.108150. Epub 2022 Feb 9. J Diabetes Complications. 2022. PMID: 35190247 Review.
This review aimed to systematically survey human studies published until 31st January 2022 for CD163 expression, in particular diabetes complications and additionally to investigate whether CD163 may be implicated as a biomarker of, and mediator in, the progression …
This review aimed to systematically survey human studies published until 31st January 2022 for CD163 expression, in particular diabet …
Role of CD163 in PRRSV infection.
Rowland RRR, Brandariz-Nuñez A. Rowland RRR, et al. Virology. 2024 Dec;600:110262. doi: 10.1016/j.virol.2024.110262. Epub 2024 Oct 16. Virology. 2024. PMID: 39423600 Free article. Review.
Extensive evidence supports CD163's essential function in PRRSV infection. This review synthesizes current knowledge about CD163's role, examining its structure-function relationship and identifying specific regions crucial for viral entry. ...Further research into …
Extensive evidence supports CD163's essential function in PRRSV infection. This review synthesizes current knowledge about CD163 …
Nanobodies against porcine CD163 as PRRSV broad inhibitor.
Deng Z, Zhang S, Sun M, Yang H, Lu Y, Wang M, Fang W, Shi F, He F. Deng Z, et al. Int J Biol Macromol. 2023 Dec 31;253(Pt 7):127493. doi: 10.1016/j.ijbiomac.2023.127493. Epub 2023 Oct 17. Int J Biol Macromol. 2023. PMID: 37858656
In this study, a phage display VHH library was constructed for the selection of Nbs against porcine CD163 scavenger receptor cysteine-rich 5-9 domain (SRCR5-9). After five rounds of bio-panning and indirect ELISA, seven CD163-specific Nbs (Nb1-Nb7) were identified. …
In this study, a phage display VHH library was constructed for the selection of Nbs against porcine CD163 scavenger receptor cysteine …
CD163 and its role in inflammation.
Kowal K, Silver R, Sławińska E, Bielecki M, Chyczewski L, Kowal-Bielecka O. Kowal K, et al. Folia Histochem Cytobiol. 2011;49(3):365-74. doi: 10.5603/fhc.2011.0052. Folia Histochem Cytobiol. 2011. PMID: 22038213 Free article. Review.
CD163-expressing mononuclear phagocytes, as well as soluble CD163, may both take part in downregulating an inflammatory response. It seems, therefore, that CD163 may be an interesting target for therapeutic modulation of the inflammatory response....
CD163-expressing mononuclear phagocytes, as well as soluble CD163, may both take part in downregulating an inflammatory respon …
CD163+ macrophages restrain vascular calcification, promoting the development of high-risk plaque.
Sakamoto A, Kawakami R, Mori M, Guo L, Paek KH, Mosquera JV, Cornelissen A, Ghosh SKB, Kawai K, Konishi T, Fernandez R, Fuller DT, Xu W, Vozenilek AE, Sato Y, Jinnouchi H, Torii S, Turner AW, Akahori H, Kuntz S, Weinkauf CC, Lee PJ, Kutys R, Harris K, Killey AL, Mayhew CM, Ellis M, Weinstein LM, Gadhoke NV, Dhingra R, Ullman J, Dikongue A, Romero ME, Kolodgie FD, Miller CL, Virmani R, Finn AV. Sakamoto A, et al. JCI Insight. 2023 Mar 8;8(5):e154922. doi: 10.1172/jci.insight.154922. JCI Insight. 2023. PMID: 36719758 Free PMC article.
Here we show, in human arteries, the distribution of CD163+ macrophages correlated inversely with VC. In vitro experiments using vascular smooth muscle cells (VSMCs) cultured with HH-exposed human macrophage - M(Hb) - supernatant reduced calcification, while arteries from …
Here we show, in human arteries, the distribution of CD163+ macrophages correlated inversely with VC. In vitro experiments using vasc …
6,216 results