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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1995 1
1996 1
2000 1
2001 2
2004 1
2005 5
2006 3
2007 4
2008 8
2009 2
2010 5
2011 10
2012 9
2013 3
2014 11
2015 13
2016 15
2017 11
2018 7
2019 11
2020 14
2021 24
2022 21
2023 4
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166 results
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Page 1
CD248 Regulates Wnt Signaling in Pericytes to Promote Angiogenesis and Tumor Growth in Lung Cancer.
Hong CL, Yu IS, Pai CH, Chen JS, Hsieh MS, Wu HL, Lin SW, Huang HP. Hong CL, et al. Cancer Res. 2022 Oct 17;82(20):3734-3750. doi: 10.1158/0008-5472.CAN-22-1695. Cancer Res. 2022. PMID: 35950912
Here, we investigated the role of stromal CD248 in lung cancer. In orthotopic lung cancer transplantation models, tumor volume, density of vessels and pericytes, and functionality of tumor vessels were all lower in mice lacking Cd248 (Cd248LacZ/LacZ) compared with …
Here, we investigated the role of stromal CD248 in lung cancer. In orthotopic lung cancer transplantation models, tumor volume, densi …
CD248: A therapeutic target in cancer and fibrotic diseases.
Teicher BA. Teicher BA. Oncotarget. 2019 Jan 29;10(9):993-1009. doi: 10.18632/oncotarget.26590. eCollection 2019 Jan 29. Oncotarget. 2019. PMID: 30847027 Free PMC article. Review.
CD248/endosialin/TEM1 is a type 1 transmembrane glycoprotein found on the plasma membrane of activated mesenchymal cells. CD248 functions during embryo development and is either not expressed or found at very low levels in adult tissues. ...
CD248/endosialin/TEM1 is a type 1 transmembrane glycoprotein found on the plasma membrane of activated mesenchymal cells. CD248 …
CD248+CD8+ T lymphocytes suppress pathological vascular remodeling in human thoracic aortic aneurysms.
Hu X, Wu T, Wang C, Li J, Ying C. Hu X, et al. Exp Biol Med (Maywood). 2021 Jan;246(2):121-129. doi: 10.1177/1535370220953386. Epub 2020 Aug 31. Exp Biol Med (Maywood). 2021. PMID: 32867546 Free PMC article.
The CD248+CD8+ T cells were characterized by upregulated IL-10 and downregulated IL-1beta/INF-gamma expression when compared with CD248-CD8+ T cells. ...This study shows that CD248 reduces pathological vascular remodeling via anti-inflammatory CD248+CD …
The CD248+CD8+ T cells were characterized by upregulated IL-10 and downregulated IL-1beta/INF-gamma expression when compared with …
Retraction: CD248 as a novel therapeutic target in pulmonary arterial hypertension.
[No authors listed] [No authors listed] Clin Transl Med. 2021 Jul;11(7):e488. doi: 10.1002/ctm2.488. Clin Transl Med. 2021. PMID: 34323428 Free PMC article.
The following article from Clinical and Translational Medicine, "CD248 as a novel therapeutic target in pulmonary arterial hypertension" by Tao Xu, Lei Shao, Aimei Wang, Rui Liang, Yuhan Lin, GuanWang, Yan Zhao, Jing Hu, and Shuangyue Liu,(1) published online on September …
The following article from Clinical and Translational Medicine, "CD248 as a novel therapeutic target in pulmonary arterial hypertensi …
Interference in melanoma CD248 function reduces vascular mimicry and metastasis.
Kuo CH, Wu YF, Chang BI, Hsu CK, Lai CH, Wu HL. Kuo CH, et al. J Biomed Sci. 2022 Nov 18;29(1):98. doi: 10.1186/s12929-022-00882-3. J Biomed Sci. 2022. PMID: 36401329 Free PMC article.
Recombinant CD248 (rCD248) proteins were generated, and whether rCD248 interfered with melanoma CD248 functions was evaluated in vitro. ...The lectin domain of CD248 was directly involved in the interaction between CD248 and fibronectin. ...
Recombinant CD248 (rCD248) proteins were generated, and whether rCD248 interfered with melanoma CD248 functions was evaluated …
CD248+ Cancer-Associated Fibroblasts: A Novel Prognostic and Therapeutic Target for Renal Cell Carcinoma.
Xu C, Zhang K, Yang F, Zhou X, Liu S, Li Y, Ma S, Zhao X, Lu T, Lu S, Zhang J, Li H, Han D, Wen W, Qin W. Xu C, et al. Front Oncol. 2021 Dec 14;11:773063. doi: 10.3389/fonc.2021.773063. eCollection 2021. Front Oncol. 2021. PMID: 34970489 Free PMC article.
Immunohistochemistry and immunofluorescence staining were performed to confirm CD248 expression within CAFs. CD248-specific siRNA was used to investigate the potential function of CD248 in CAF tumor promotion. ...CD248 may serve as a promising CAFs bio …
Immunohistochemistry and immunofluorescence staining were performed to confirm CD248 expression within CAFs. CD248-specific si …
Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis.
Pai CH, Lin SR, Liu CH, Pan SY, Hsu H, Chen YT, Yen CT, Yu IS, Wu HL, Lin SL, Lin SW. Pai CH, et al. Sci Rep. 2020 Oct 8;10(1):16772. doi: 10.1038/s41598-020-73194-x. Sci Rep. 2020. PMID: 33033277 Free PMC article.
Cd248 knockout (Cd248(-/-)) could attenuate both renal and peritoneal fibrosis. ...Mice with DNA vaccination targeting CD248 showed decreased fibrosis. We thus propose that CD248 targeting should be studied in the clinical tissue fibrosis setting....
Cd248 knockout (Cd248(-/-)) could attenuate both renal and peritoneal fibrosis. ...Mice with DNA vaccination targeting CD24 …
CD248: reviewing its role in health and disease.
Valdez Y, Maia M, Conway EM. Valdez Y, et al. Curr Drug Targets. 2012 Mar;13(3):432-9. doi: 10.2174/138945012799424615. Curr Drug Targets. 2012. PMID: 22206249 Review.
In spite of these advances, the mechanisms by which CD248 modulates cancer and inflammation remain largely enigmatic. This review highlights our current understanding of CD248, its structure, pattern of expression, regulation and function in various disease processe …
In spite of these advances, the mechanisms by which CD248 modulates cancer and inflammation remain largely enigmatic. This review hig …
CD248 as a novel therapeutic target in pulmonary arterial hypertension.
Xu T, Shao L, Wang A, Liang R, Lin Y, Wang G, Zhao Y, Hu J, Liu S. Xu T, et al. Clin Transl Med. 2020 Sep;10(5):e175. doi: 10.1002/ctm2.175. Clin Transl Med. 2020. PMID: 32997414 Free PMC article. Retracted.
Here, we evaluated the role of CD248 in pulmonary vascular remodeling and the processes of PAH pathogenesis. ...In addition, knockdown of CD248 alleviated pulmonary vascular remodeling in rat PAH models. ...
Here, we evaluated the role of CD248 in pulmonary vascular remodeling and the processes of PAH pathogenesis. ...In addition, knockdow …
CD248 as a bridge between angiogenesis and immunosuppression: a promising prognostic and therapeutic target for renal cell carcinoma.
Liu S, Xu C, Zhang K, Han D, Yang F, Li Y, Zhao X, Ma S, Li H, Lu S, Lu T, Zhang J, Qin W, Wen W, Yang B. Liu S, et al. Ann Transl Med. 2021 Dec;9(23):1741. doi: 10.21037/atm-21-6271. Ann Transl Med. 2021. PMID: 35071435 Free PMC article.
CD248-based drug response was predicted through CellMiner database. ...CD248-based medication guidance might benefit RCC patients....
CD248-based drug response was predicted through CellMiner database. ...CD248-based medication guidance might benefit RCC patie …
166 results