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4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. Among authors: celanire s. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114
Lead optimization of thiazolo[5,4-c]piperidines: 3-cyclobutoxy linker as a key spacer for H(3)R inverse agonists.
Provins L, Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Demaude T, Durieu V, Gillard M, Hubert D, Lamberty Y, Lorent G, Valade A, Vanbellinghen A, Van Houtvin N. Provins L, et al. Among authors: celanire s. ChemMedChem. 2012 Dec;7(12):2087-92. doi: 10.1002/cmdc.201200406. Epub 2012 Oct 5. ChemMedChem. 2012. PMID: 23042668
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells.
Volpi C, Mondanelli G, Pallotta MT, Vacca C, Iacono A, Gargaro M, Albini E, Bianchi R, Belladonna ML, Celanire S, Mordant C, Heroux M, Royer-Urios I, Schneider M, Vitte PA, Cacquevel M, Galibert L, Poli SM, Solari A, Bicciato S, Calvitti M, Antognelli C, Puccetti P, Orabona C, Fallarino F, Grohmann U. Volpi C, et al. Among authors: celanire s. Neuropharmacology. 2016 Mar;102:59-71. doi: 10.1016/j.neuropharm.2015.10.036. Epub 2015 Oct 30. Neuropharmacology. 2016. PMID: 26522434 Free PMC article.
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
14 results