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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 4
1990 27
1991 105
1992 219
1993 217
1994 248
1995 296
1996 303
1997 308
1998 310
1999 356
2000 382
2001 416
2002 387
2003 359
2004 452
2005 410
2006 392
2007 385
2008 417
2009 402
2010 463
2011 497
2012 517
2013 501
2014 507
2015 559
2016 543
2017 529
2018 590
2019 640
2020 738
2021 802
2022 867
2023 815
2024 771
2025 896
2026 210

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15,147 results

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Page 1
Cystic fibrosis: Epidemiology, clinical manifestations, diagnosis and treatment.
Diab Cáceres L, Zamarrón de Lucas E. Diab Cáceres L, et al. Med Clin (Barc). 2023 Nov 10;161(9):389-396. doi: 10.1016/j.medcli.2023.06.006. Epub 2023 Aug 7. Med Clin (Barc). 2023. PMID: 37558605 Review. English, Spanish.
Until a decade ago, treatments were aimed at favoring secretion drainage, reducing respiratory exacerbations, controlling chronic bronchial infection and slowing functional deterioration, but with the advent of cystic fibrosis transmembrane conductance regulator (CFTR) mod …
Until a decade ago, treatments were aimed at favoring secretion drainage, reducing respiratory exacerbations, controlling chronic bronchial …
CFTR structure.
Callebaut I, Chong PA, Forman-Kay JD. Callebaut I, et al. J Cyst Fibros. 2018 Mar;17(2S):S5-S8. doi: 10.1016/j.jcf.2017.08.008. Epub 2017 Aug 31. J Cyst Fibros. 2018. PMID: 28866450 Free article. Review.
Structural studies of the cystic fibrosis transmembrane conductance regulator (CFTR) protein are critical to understand molecular mechanisms involved in gating of the apical anion channel as well as the way in which the gating is regulated, especially by the regulatory reg …
Structural studies of the cystic fibrosis transmembrane conductance regulator (CFTR) protein are critical to understand molecular mec …
Splicing mutations in the CFTR gene as therapeutic targets.
Deletang K, Taulan-Cadars M. Deletang K, et al. Gene Ther. 2022 Aug;29(7-8):399-406. doi: 10.1038/s41434-022-00347-0. Epub 2022 Jun 2. Gene Ther. 2022. PMID: 35650428 Free PMC article. Review.
The marketing approval, about ten years ago, of the first disease modulator for patients with cystic fibrosis harboring specific CFTR genotypes (~5% of all patients) brought new hope for their treatment. To date, several therapeutic strategies have been approved and the nu …
The marketing approval, about ten years ago, of the first disease modulator for patients with cystic fibrosis harboring specific CFTR …
Discovering CFTR modulators.
Crunkhorn S. Crunkhorn S. Nat Rev Drug Discov. 2024 Aug;23(8):581. doi: 10.1038/d41573-024-00112-5. Nat Rev Drug Discov. 2024. PMID: 38937614 No abstract available.
CFTR modulator therapies - Effect on life expectancy in people with cystic fibrosis.
Balfour-Lynn IM, King JA. Balfour-Lynn IM, et al. Paediatr Respir Rev. 2022 Jun;42:3-8. doi: 10.1016/j.prrv.2020.05.002. Epub 2020 May 26. Paediatr Respir Rev. 2022. PMID: 32565113 Free PMC article. Review.
CFTR modulators have dramatically changed the clinical course of CF in those fortunate enough to receive them. ...
CFTR modulators have dramatically changed the clinical course of CF in those fortunate enough to receive them. ...
CFTR Modulators for the Gastroenterologist.
Sabharwal S, Lusman SS. Sabharwal S, et al. J Pediatr Gastroenterol Nutr. 2023 Oct 1;77(4):445-447. doi: 10.1097/MPG.0000000000003904. Epub 2023 Aug 7. J Pediatr Gastroenterol Nutr. 2023. PMID: 37548477 No abstract available.
An Update on CFTR Drug Discovery: Opportunities and Challenges.
D'Ursi P, Fossa P. D'Ursi P, et al. Biomolecules. 2022 Jun 6;12(6):792. doi: 10.3390/biom12060792. Biomolecules. 2022. PMID: 35740917 Free PMC article.
The Biomolecules Special issue on "An Update on CFTR Drug Discovery: Opportunities and Challenges" includes three original research articles and a webinar session focusing on some recent findings concerning CFTR drug discovery [...]....
The Biomolecules Special issue on "An Update on CFTR Drug Discovery: Opportunities and Challenges" includes three original research a …
Antibodies for CFTR studies.
Mendes F, Farinha CM, Roxo-Rosa M, Fanen P, Edelman A, Dormer R, McPherson M, Davidson H, Puchelle E, De Jonge H, Heda GD, Gentzsch M, Lukacs G, Penque D, Amaral MD. Mendes F, et al. J Cyst Fibros. 2004 Aug;3 Suppl 2:69-72. doi: 10.1016/j.jcf.2004.05.016. J Cyst Fibros. 2004. PMID: 15463931 Free article. Review.
For most expression studies focusing on the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, sensitive and specific antibodies (Abs) are critically needed. Several Abs have been produced commercially or by research laboratories for CFTR detection …
For most expression studies focusing on the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, sensitive and specifi …
15,147 results
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