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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2.

Chan KK, Dorosky D, Sharma P, Abbasi SA, Dye JM, Kranz DM, Herbert AS, Procko E. Chan KK, et al. Science. 2020 Sep 4;369(6508):1261-1265. doi: 10.1126/science.abc0870. Epub 2020 Aug 4. Science. 2020. PMID: 32753553 Free PMC article.

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The Impact of the Tumor Microenvironment on Macrophage Polarization in Cancer Metastatic Progression.

Wang H, Yung MMH, Ngan HYS, Chan KKL, Chan DW. Wang H, et al. Among authors: chan kkl. Int J Mol Sci. 2021 Jun 18;22(12):6560. doi: 10.3390/ijms22126560. Int J Mol Sci. 2021. PMID: 34207286 Free PMC article. Review.

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Clinic-Based Patellar Mobilization Therapy for Knee Osteoarthritis: A Randomized Clinical Trial.

Sit RWS, Chan KKW, Zou D, Chan DCC, Yip BHK, Zhang DD, Chan YH, Chung VCH, Reeves KD, Wong SYS. Sit RWS, et al. Among authors: chan kkw. Ann Fam Med. 2018 Nov;16(6):521-529. doi: 10.1370/afm.2320. Ann Fam Med. 2018. PMID: 30420367 Free PMC article. Clinical Trial.

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The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis.

Kuksis M, Gao Y, Tran W, Hoey C, Kiss A, Komorowski AS, Dhaliwal AJ, Sahgal A, Das S, Chan KK, Jerzak KJ. Kuksis M, et al. Among authors: chan kk. Neuro Oncol. 2021 Jun 1;23(6):894-904. doi: 10.1093/neuonc/noaa285. Neuro Oncol. 2021. PMID: 33367836 Free PMC article.

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Rectal Vascular Malformation.

Muniandy J, Chan KK, Bakin S. Muniandy J, et al. Among authors: chan kk. J Gastrointest Surg. 2021 Oct;25(10):2715-2717. doi: 10.1007/s11605-021-05002-4. Epub 2021 Apr 8. J Gastrointest Surg. 2021. PMID: 33834378 No abstract available.

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MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis.

Chan DW, Yung MM, Chan YS, Xuan Y, Yang H, Xu D, Zhan JB, Chan KK, Ng TB, Ngan HY. Chan DW, et al. Among authors: chan kk. Pharmacol Res. 2020 Nov;161:105157. doi: 10.1016/j.phrs.2020.105157. Epub 2020 Aug 16. Pharmacol Res. 2020. PMID: 32814169 Free article.

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Chest ultrasonography versus supine chest radiography for diagnosis of pneumothorax in trauma patients in the emergency department.

Chan KK, Joo DA, McRae AD, Takwoingi Y, Premji ZA, Lang E, Wakai A. Chan KK, et al. Cochrane Database Syst Rev. 2020 Jul 23;7(7):CD013031. doi: 10.1002/14651858.CD013031.pub2. Cochrane Database Syst Rev. 2020. PMID: 32702777 Free PMC article.

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Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination.

Cheng SMS, Mok CKP, Leung YWY, Ng SS, Chan KCK, Ko FW, Chen C, Yiu K, Lam BHS, Lau EHY, Chan KKP, Luk LLH, Li JKC, Tsang LCH, Poon LLM, Hui DSC, Peiris M. Cheng SMS, et al. Among authors: chan kkp. Nat Med. 2022 Mar;28(3):486-489. doi: 10.1038/s41591-022-01704-7. Epub 2022 Jan 20. Nat Med. 2022. PMID: 35051989 Free PMC article.

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Novel SLOFT technique.

Raja Ram NK, Chan KK, Fareeda S, Sagap I. Raja Ram NK, et al. Among authors: chan kk. Colorectal Dis. 2020 Dec;22(12):2334-2335. doi: 10.1111/codi.15370. Epub 2020 Oct 25. Colorectal Dis. 2020. PMID: 32946673 No abstract available.

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Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants.

Zhang L, Dutta S, Xiong S, Chan M, Chan KK, Fan TM, Bailey KL, Lindeblad M, Cooper LM, Rong L, Gugliuzza AF, Shukla D, Procko E, Rehman J, Malik AB. Zhang L, et al. Among authors: chan kk. Nat Chem Biol. 2022 Mar;18(3):342-351. doi: 10.1038/s41589-021-00965-6. Epub 2022 Jan 19. Nat Chem Biol. 2022. PMID: 35046611 Free PMC article.

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