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Year Number of Results
2004 1
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31 results

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Page 1
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT. McArthur K, et al. Among authors: chappaz s. Science. 2018 Feb 23;359(6378):eaao6047. doi: 10.1126/science.aao6047. Science. 2018. PMID: 29472455
Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling.
Nikolic I, Cursons J, Shields B, Chappaz S, Sudholz H, Meng X, Constantinescu P, Vijayakumaran R, D'Angelo M, Foroutan M, Ladd D, Veldman M, Glab J, Procter T, Park HY, Contet J, Deuss F, Wong K, Sun Y, Berry R, Rautela J, Huntington ND. Nikolic I, et al. Among authors: chappaz s. Cancer Cell. 2025 Nov 10;43(11):2034-2050.e11. doi: 10.1016/j.ccell.2025.05.011. Epub 2025 Jun 12. Cancer Cell. 2025. PMID: 40513576
Venetoclax dose escalation rapidly activates a BAFF/BCL-2 survival axis in chronic lymphocytic leukemia.
Luo MX, Tan T, Trussart M, Poch A, Nguyen TMH, Speed TP, Hicks DG, Bandala-Sanchez E, Peng H, Chappaz S, Slade C, Utzschneider DT, Koldej RM, Ritchie D, Strasser A, Thijssen R, Ritchie ME, Tam CS, Lindeman GJ, Huang DCS, Lew TE, Anderson MA, Roberts AW, Teh CE, Gray DHD. Luo MX, et al. Among authors: chappaz s. Blood. 2024 Dec 26;144(26):2748-2761. doi: 10.1182/blood.2024024341. Blood. 2024. PMID: 39471335 Free PMC article.
Yeast- and antibody-based tools for studying tryptophan C-mannosylation.
John A, Järvå MA, Shah S, Mao R, Chappaz S, Birkinshaw RW, Czabotar PE, Lo AW, Scott NE, Goddard-Borger ED. John A, et al. Among authors: chappaz s. Nat Chem Biol. 2021 Apr;17(4):428-437. doi: 10.1038/s41589-020-00727-w. Epub 2021 Feb 4. Nat Chem Biol. 2021. PMID: 33542533
An essential role for α4A-tubulin in platelet biogenesis.
Strassel C, Magiera MM, Dupuis A, Batzenschlager M, Hovasse A, Pleines I, Guéguen P, Eckly A, Moog S, Mallo L, Kimmerlin Q, Chappaz S, Strub JM, Kathiresan N, de la Salle H, Van Dorsselaer A, Ferec C, Py JY, Gachet C, Schaeffer-Reiss C, Kile BT, Janke C, Lanza F. Strassel C, et al. Among authors: chappaz s. Life Sci Alliance. 2019 Feb 13;2(1):e201900309. doi: 10.26508/lsa.201900309. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30760556 Free PMC article.
VDAC2 enables BAX to mediate apoptosis and limit tumor development.
Chin HS, Li MX, Tan IKL, Ninnis RL, Reljic B, Scicluna K, Dagley LF, Sandow JJ, Kelly GL, Samson AL, Chappaz S, Khaw SL, Chang C, Morokoff A, Brinkmann K, Webb A, Hockings C, Hall CM, Kueh AJ, Ryan MT, Kluck RM, Bouillet P, Herold MJ, Gray DHD, Huang DCS, van Delft MF, Dewson G. Chin HS, et al. Among authors: chappaz s. Nat Commun. 2018 Nov 26;9(1):4976. doi: 10.1038/s41467-018-07309-4. Nat Commun. 2018. PMID: 30478310 Free PMC article.
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis.
van Delft MF, Chappaz S, Khakham Y, Bui CT, Debrincat MA, Lowes KN, Brouwer JM, Grohmann C, Sharp PP, Dagley LF, Li L, McArthur K, Luo MX, Chin HS, Fairlie WD, Lee EF, Segal D, Duflocq S, Lessene R, Bernard S, Peilleron L, Nguyen T, Miles C, Wan SS, Lane RM, Wardak A, Lackovic K, Colman PM, Sandow JJ, Webb AI, Czabotar PE, Dewson G, Watson KG, Huang DCS, Lessene G, Kile BT. van Delft MF, et al. Among authors: chappaz s. Nat Chem Biol. 2019 Nov;15(11):1057-1066. doi: 10.1038/s41589-019-0365-8. Epub 2019 Oct 7. Nat Chem Biol. 2019. PMID: 31591564
Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses.
von Burg N, Chappaz S, Baerenwaldt A, Horvath E, Bose Dasgupta S, Ashok D, Pieters J, Tacchini-Cottier F, Rolink A, Acha-Orbea H, Finke D. von Burg N, et al. Among authors: chappaz s. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12835-40. doi: 10.1073/pnas.1406908111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136120 Free PMC article.
31 results