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Page 1
Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial.
Isenberg D, Furie R, Jones NS, Guibord P, Galanter J, Lee C, McGregor A, Toth B, Rae J, Hwang O, Desai R, Lokku A, Ramamoorthi N, Hackney JA, Miranda P, de Souza VA, Jaller-Raad JJ, Maura Fernandes A, Garcia Salinas R, Chinn LW, Townsend MJ, Morimoto AM, Tuckwell K. Isenberg D, et al. Among authors: chinn lw. Arthritis Rheumatol. 2021 Oct;73(10):1835-1846. doi: 10.1002/art.41811. Epub 2021 Aug 24. Arthritis Rheumatol. 2021. PMID: 34042314 Clinical Trial.
Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein).
Hodges LM, Markova SM, Chinn LW, Gow JM, Kroetz DL, Klein TE, Altman RB. Hodges LM, et al. Among authors: chinn lw. Pharmacogenet Genomics. 2011 Mar;21(3):152-61. doi: 10.1097/FPC.0b013e3283385a1c. Pharmacogenet Genomics. 2011. PMID: 20216335 Free PMC article. No abstract available.
Substrate-dependent effects of human ABCB1 coding polymorphisms.
Gow JM, Hodges LM, Chinn LW, Kroetz DL. Gow JM, et al. Among authors: chinn lw. J Pharmacol Exp Ther. 2008 May;325(2):435-42. doi: 10.1124/jpet.107.135194. Epub 2008 Feb 20. J Pharmacol Exp Ther. 2008. PMID: 18287207 Free PMC article.
Antibody-mediated activation of the FGFR1/Klothoβ complex corrects metabolic dysfunction and alters food preference in obese humans.
Baruch A, Wong C, Chinn LW, Vaze A, Sonoda J, Gelzleichter T, Chen S, Lewin-Koh N, Morrow L, Dheerendra S, Boismenu R, Gutierrez J, Wakshull E, Wilson ME, Arora PS. Baruch A, et al. Among authors: chinn lw. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28992-29000. doi: 10.1073/pnas.2012073117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139537 Free PMC article. Clinical Trial.
21 results