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69 results

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Page 1
Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early Discovery.
Mandal M, Madeira M, Amin RP, Buevich AV, Cheng A, Labroli M, Liu X, Acton J, Pio B, Basso A, Chobanian H, Dong G, Dropinski J, Guo Y, Guo Z, Kurowski S, Korfmacher W, Lee S, Meng D, Ondeyka D, Yang Z, Zhang R, Wei H, Wu Z, Zhang F, Wollenberg G, Biftu T, Greenlee WJ, Chintala M, Maletic M, Zhu Z. Mandal M, et al. Among authors: chintala m. J Med Chem. 2022 Apr 14;65(7):5575-5592. doi: 10.1021/acs.jmedchem.1c02048. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35349275
Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.
Xu G, Liu Z, Wang X, Lu T, DesJarlais RL, Thieu T, Zhang J, Devine ZH, Du F, Li Q, Milligan CM, Shaffer P, Cedervall PE, Spurlino JC, Stratton CF, Pietrak B, Szewczuk LM, Wong V, Steele RA, Bruinzeel W, Chintala M, Silva J, Gaul MD, Macielag MJ, Nargund R. Xu G, et al. Among authors: chintala m. J Med Chem. 2022 Aug 11;65(15):10419-10440. doi: 10.1021/acs.jmedchem.2c00442. Epub 2022 Jul 21. J Med Chem. 2022. PMID: 35862732
Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications.
Putta S, Peluso I, Yarla NS, Kilari EK, Bishayee A, Lu DY, Barreto GE, Ashraf GM, Scotti L, Scotti MT, Singla RK, Alexiou T, Atanasov AG, Tarasov VV, Bramhachari PV, Imandi SB, Chintala M, Sharma B, Reale M, Filosa R, Aliev G, Kamal MA. Putta S, et al. Among authors: chintala m. Curr Pharm Des. 2017;23(30):4475-4483. doi: 10.2174/1381612823666170823103830. Curr Pharm Des. 2017. PMID: 28831925
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors.
McKittrick BA, Caldwell JP, Bara T, Boykow G, Chintala M, Clader J, Czarniecki M, Courneya B, Duffy R, Fleming L, Giessert R, Greenlee WJ, Heap C, Hong L, Huang Y, Iserloh U, Josien H, Khan T, Korfmacher W, Liang X, Mazzola R, Mitra S, Moore K, Orth P, Rajagopalan M, Roy S, Sakwa S, Strickland C, Vaccaro H, Voigt J, Wang H, Wong J, Zhang R, Zych A. McKittrick BA, et al. Among authors: chintala m. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1592-6. doi: 10.1016/j.bmcl.2015.02.003. Epub 2015 Feb 10. Bioorg Med Chem Lett. 2015. PMID: 25728416
Resilience of aquatic systems: Review and management implications.
Pelletier MC, Ebersole J, Mulvaney K, Rashleigh B, Gutierrez MN, Chintala M, Kuhn A, Molina M, Bagley M, Lane C. Pelletier MC, et al. Among authors: chintala m. Aquat Sci. 2020 Mar 28;82(2):1-44. doi: 10.1007/s00027-020-00717-z. Aquat Sci. 2020. PMID: 32489242 Free PMC article.
69 results