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Showing results for chiral p[au]
Your search for Chirag P[au] retrieved no results
Advances and challenges in the pharmacokinetics and bioanalysis of chiral drugs.
Kumari Rayala VVSP, Kandula JS, P R. Kumari Rayala VVSP, et al. Among authors: p r. Chirality. 2022 Oct;34(10):1298-1310. doi: 10.1002/chir.23495. Epub 2022 Jul 26. Chirality. 2022. PMID: 35883279 Review.
Challenges such as lack of universal chiral columns, biological inversion of the isomers, and others have been discussed. Further presented the recent advances in the screening of chiral drugs and innovative improvements in the analytical approaches for chiral …
Challenges such as lack of universal chiral columns, biological inversion of the isomers, and others have been discussed. Further pre …
A validated chiral chromatographic method for the enantiomeric separation of acalabrutinib.
Rayala VVSPK, Trivedi KA, Upadhyayula SM, Gunnam S, Borkar RM, P R. Rayala VVSPK, et al. Among authors: p r. Chirality. 2022 Sep;34(9):1247-1256. doi: 10.1002/chir.23485. Epub 2022 Jun 21. Chirality. 2022. PMID: 35727097
Acalabrutinib belongs to the imidazopyrazine class consisting of a chiral carbon, resulting in two enantiomers. Currently, no methods exist for the separation and quantification of these enantiomers. A novel and selective enantiomeric chromatographic technique has been est …
Acalabrutinib belongs to the imidazopyrazine class consisting of a chiral carbon, resulting in two enantiomers. Currently, no methods …
Transition metal-free catalytic reduction of primary amides using an abnormal NHC based potassium complex: integrating nucleophilicity with Lewis acidic activation.
Bhunia M, Sahoo SR, Das A, Ahmed J, P S, Mandal SK. Bhunia M, et al. Among authors: p s. Chem Sci. 2019 Dec 27;11(7):1848-1854. doi: 10.1039/c9sc05953a. Chem Sci. 2019. PMID: 34123278 Free PMC article.
Only 2 mol% loading of the catalyst exhibits a broad substrate scope including aromatic, aliphatic and heterocyclic primary amides with excellent functional group tolerance. This method was applicable for reduction of chiral amides and utilized for the synthesis of pharmac …
Only 2 mol% loading of the catalyst exhibits a broad substrate scope including aromatic, aliphatic and heterocyclic primary amides with exce …