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Year Number of Results
1997 1
2002 20
2003 18
2004 12
2005 19
2006 14
2007 14
2008 16
2009 22
2010 37
2011 29
2012 27
2013 23
2014 37
2015 31
2016 32
2017 23
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2019 36
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2021 43
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2023 33
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571 results

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Page 1
2-Oxoglutarate-Dependent Oxygenases.
Islam MS, Leissing TM, Chowdhury R, Hopkinson RJ, Schofield CJ. Islam MS, et al. Among authors: schofield cj. Annu Rev Biochem. 2018 Jun 20;87:585-620. doi: 10.1146/annurev-biochem-061516-044724. Epub 2018 Mar 1. Annu Rev Biochem. 2018. PMID: 29494239 Review.
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, MacLean … See abstract for full author list ➔ Boby ML, et al. Among authors: schofield cj. Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. Science. 2023. PMID: 37943932 Free PMC article.
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia.
Lawson H, Holt-Martyn JP, Dembitz V, Kabayama Y, Wang LM, Bellani A, Atwal S, Saffoon N, Durko J, van de Lagemaat LN, De Pace AL, Tumber A, Corner T, Salah E, Arndt C, Brewitz L, Bowen M, Dubusse L, George D, Allen L, Guitart AV, Fung TK, So CWE, Schwaller J, Gallipoli P, O'Carroll D, Schofield CJ, Kranc KR. Lawson H, et al. Among authors: schofield cj. Nat Cancer. 2024 Jun;5(6):916-937. doi: 10.1038/s43018-024-00761-w. Epub 2024 Apr 18. Nat Cancer. 2024. PMID: 38637657 Free PMC article.
ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma.
Lu Y, Travnickova J, Badonyi M, Rambow F, Coates A, Khan Z, Marques J, Murphy LC, Garcia-Martinez P, Marais R, Louphrasitthiphol P, Chan AHY, Schofield CJ, von Kriegsheim A, Marsh JA, Pavet V, Sansom OJ, Illingworth RS, Patton EE. Lu Y, et al. Among authors: schofield cj. Cell Rep. 2024 Jul 23;43(7):114406. doi: 10.1016/j.celrep.2024.114406. Epub 2024 Jul 3. Cell Rep. 2024. PMID: 38963759 Free PMC article.
Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality.
Wang R, Gomez Salazar M, Pruñonosa Cervera I, Coutts A, French K, Pinto MM, Gohlke S, García-Martín R, Blüher M, Schofield CJ, Kourtzelis I, Stimson RH, Bénézech C, Christian M, Schulz TJ, Gudmundsson EF, Jennings LL, Gudnason VG, Chavakis T, Morton NM, Emilsson V, Michailidou Z. Wang R, et al. Among authors: schofield cj. Nat Commun. 2024 Aug 29;15(1):7483. doi: 10.1038/s41467-024-51718-7. Nat Commun. 2024. PMID: 39209825 Free PMC article.
Biochemistry of the hypoxia-inducible factor hydroxylases.
Fiorini G, Schofield CJ. Fiorini G, et al. Among authors: schofield cj. Curr Opin Chem Biol. 2024 Apr;79:102428. doi: 10.1016/j.cbpa.2024.102428. Epub 2024 Feb 7. Curr Opin Chem Biol. 2024. PMID: 38330792 Free article. Review.
The SNM1A DNA repair nuclease.
Baddock HT, Yosaatmadja Y, Newman JA, Schofield CJ, Gileadi O, McHugh PJ. Baddock HT, et al. Among authors: schofield cj. DNA Repair (Amst). 2020 Nov;95:102941. doi: 10.1016/j.dnarep.2020.102941. Epub 2020 Jul 31. DNA Repair (Amst). 2020. PMID: 32866775 Free PMC article. Review.
Recent Progress in Histone Demethylase Inhibitors.
McAllister TE, England KS, Hopkinson RJ, Brennan PE, Kawamura A, Schofield CJ. McAllister TE, et al. Among authors: schofield cj. J Med Chem. 2016 Feb 25;59(4):1308-29. doi: 10.1021/acs.jmedchem.5b01758. Epub 2016 Feb 2. J Med Chem. 2016. PMID: 26710088 Review.
SNM1A is crucial for efficient repair of complex DNA breaks in human cells.
Swift LP, Lagerholm BC, Henderson LR, Ratnaweera M, Baddock HT, Sengerova B, Lee S, Cruz-Migoni A, Waithe D, Renz C, Ulrich HD, Newman JA, Schofield CJ, McHugh PJ. Swift LP, et al. Among authors: schofield cj. Nat Commun. 2024 Jun 25;15(1):5392. doi: 10.1038/s41467-024-49583-5. Nat Commun. 2024. PMID: 38918391 Free PMC article.
Will morphing boron-based inhibitors beat the β-lactamases?
Krajnc A, Lang PA, Panduwawala TD, Brem J, Schofield CJ. Krajnc A, et al. Among authors: schofield cj. Curr Opin Chem Biol. 2019 Jun;50:101-110. doi: 10.1016/j.cbpa.2019.03.001. Epub 2019 Apr 18. Curr Opin Chem Biol. 2019. PMID: 31004962 Free PMC article. Review.
571 results