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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1988 1
1990 1
1992 1
1993 1
1994 1
1995 1
1996 1
1997 6
1998 5
1999 8
2000 5
2001 7
2002 6
2003 7
2004 10
2005 9
2006 12
2007 10
2008 18
2009 15
2010 19
2011 22
2012 26
2013 29
2014 32
2015 25
2016 35
2017 22
2018 44
2019 21
2020 21
2021 25
2022 20
2023 21
2024 5

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430 results

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Page 1
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: christopoulos a. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Free article. Clinical Trial.
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Zhang X, et al. Among authors: christopoulos a. Mol Cell. 2020 Nov 5;80(3):485-500.e7. doi: 10.1016/j.molcel.2020.09.020. Epub 2020 Oct 6. Mol Cell. 2020. PMID: 33027691 Free article.
The role of the adenosine system in epilepsy and its comorbidities.
Baltos JA, Casillas-Espinosa PM, Rollo B, Gregory KJ, White PJ, Christopoulos A, Kwan P, O'Brien TJ, May LT. Baltos JA, et al. Among authors: christopoulos a. Br J Pharmacol. 2023 Apr 19. doi: 10.1111/bph.16094. Online ahead of print. Br J Pharmacol. 2023. PMID: 37076128 Free article. Review.
Structural insights into G-protein-coupled receptor allostery.
Thal DM, Glukhova A, Sexton PM, Christopoulos A. Thal DM, et al. Among authors: christopoulos a. Nature. 2018 Jul;559(7712):45-53. doi: 10.1038/s41586-018-0259-z. Epub 2018 Jul 4. Nature. 2018. PMID: 29973731 Review.
mTOR as a senescence manipulation target: A forked road.
Saoudaoui S, Bernard M, Cardin GB, Malaquin N, Christopoulos A, Rodier F. Saoudaoui S, et al. Among authors: christopoulos a. Adv Cancer Res. 2021;150:335-363. doi: 10.1016/bs.acr.2021.02.002. Epub 2021 Mar 18. Adv Cancer Res. 2021. PMID: 33858600 Review.
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia.
Draper-Joyce CJ, Bhola R, Wang J, Bhattarai A, Nguyen ATN, Cowie-Kent I, O'Sullivan K, Chia LY, Venugopal H, Valant C, Thal DM, Wootten D, Panel N, Carlsson J, Christie MJ, White PJ, Scammells P, May LT, Sexton PM, Danev R, Miao Y, Glukhova A, Imlach WL, Christopoulos A. Draper-Joyce CJ, et al. Among authors: christopoulos a. Nature. 2021 Sep;597(7877):571-576. doi: 10.1038/s41586-021-03897-2. Epub 2021 Sep 8. Nature. 2021. PMID: 34497422 Free PMC article.
A structural basis for amylin receptor phenotype.
Cao J, Belousoff MJ, Liang YL, Johnson RM, Josephs TM, Fletcher MM, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. Cao J, et al. Among authors: christopoulos a. Science. 2022 Mar 25;375(6587):eabm9609. doi: 10.1126/science.abm9609. Epub 2022 Mar 25. Science. 2022. PMID: 35324283
430 results