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Page 1
Enzyme assay of sulfotransferase for HNK-1 epitope (HNK-1ST, CHST10).
Kizuka Y, Morise J, Oka S. Kizuka Y, et al. 2021 Sep 7 [updated 2022 Mar 14]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. 2021 Sep 7 [updated 2022 Mar 14]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. PMID: 37590598 Free Books & Documents. Review. No abstract available.
In vivo regulation of steroid hormones by the Chst10 sulfotransferase in mouse.
Suzuki-Anekoji M, Suzuki A, Wu SW, Angata K, Murai KK, Sugihara K, Akama TO, Khoo KH, Nakayama J, Fukuda MN, Fukuda M. Suzuki-Anekoji M, et al. J Biol Chem. 2013 Feb 15;288(7):5007-16. doi: 10.1074/jbc.M112.433474. Epub 2012 Dec 26. J Biol Chem. 2013. PMID: 23269668 Free PMC article.
To determine the role of Chst10 in vivo, we generated systemic Chst10-deficient mutant mice. Although Chst10(-/-) mice were born and grew to adulthood with no gross defects, they were subfertile. ...These results suggest that subfertility exhibited by female …
To determine the role of Chst10 in vivo, we generated systemic Chst10-deficient mutant mice. Although Chst10(-/-) mice …
Mating Increases CHST10 Activity in Rat Oviductal Mucosa to Induce the Synthesis of HNK-1 Glycoproteins: Possible Role in Sperm-Oviduct Interactions.
Fábrega-Guerén F, Andrade JC, Zúñiga-Cóndor M, Morales P, Gómez-Silva B, Zúñiga LM. Fábrega-Guerén F, et al. Int J Mol Sci. 2025 Apr 2;26(7):3309. doi: 10.3390/ijms26073309. Int J Mol Sci. 2025. PMID: 40244179 Free PMC article.
Therefore, in the present study, we describe the role of one of these genes, carbohydrate sulfotransferase 10 (Chst10), in the oviductal mucosa. CHST10 participates in the synthesis of the carbohydrate moiety human natural killer-1 (HNK-1), which mediates cell-to-ce …
Therefore, in the present study, we describe the role of one of these genes, carbohydrate sulfotransferase 10 (Chst10), in the oviduc …
Mechanism of regulation and suppression of melanoma invasiveness by novel retinoic acid receptor-gamma target gene carbohydrate sulfotransferase 10.
Zhao X, Graves C, Ames SJ, Fisher DE, Spanjaard RA. Zhao X, et al. Cancer Res. 2009 Jun 15;69(12):5218-25. doi: 10.1158/0008-5472.CAN-09-0705. Epub 2009 May 26. Cancer Res. 2009. PMID: 19470764
Here, we identified and validated carbohydrate sulfotransferase 10 (CHST10) as a novel RARgamma target gene in S91 cells. The RARgamma-inducible CHST10 promoter was obtained, and two atypical, independently functioning RA response elements were identified in a 425 b …
Here, we identified and validated carbohydrate sulfotransferase 10 (CHST10) as a novel RARgamma target gene in S91 cells. The RARgamm …
Pathogenic mechanisms and clinical insights into B3GALNT2-related alpha-dystroglycanopathies.
Fu X, Wang H, Chai W, Chen X, Song D, Wang W, Zhong J, Liu Z, Tong X, Xiong H, Ren X, Gui J. Fu X, et al. J Neuromuscul Dis. 2025 Nov;12(6):814-827. doi: 10.1177/22143602251360270. Epub 2025 Jul 15. J Neuromuscul Dis. 2025. PMID: 40665687 Free article.
Transcriptomic analysis revealed upregulation of CHST10 in two patients.ConclusionsThis study expands the mutational spectrum of B3GALNT2-related alpha-DGP and provides mechanistic insight into the pathogenicity of novel variants. Our findings support a functional threshol …
Transcriptomic analysis revealed upregulation of CHST10 in two patients.ConclusionsThis study expands the mutational spectrum of B3GA …
What happens to the osteoporotic bone mesenchymal stem cells? Evidence from RNA sequencing.
Li M, Cong R, Wang H, Ma C, Lv Y, Zheng Y, Zhao Y, Fu Q, Li L. Li M, et al. Int J Med Sci. 2024 Jan 1;21(1):95-106. doi: 10.7150/ijms.88146. eCollection 2024. Int J Med Sci. 2024. PMID: 38164361 Free PMC article.
Part of the findings were verified that seven mRNAs (Abi3bp, Aifm3, Ccl11, Cdkn1c, Chst10, Id2, Vcam1) were significantly up-regulated in osteoporotic BMSCs while seven mRNAs (Cep63, Fgfr3, Myc, Omd, Pou2f1, Smarcal1, Timm10b) were down-regulated. ...
Part of the findings were verified that seven mRNAs (Abi3bp, Aifm3, Ccl11, Cdkn1c, Chst10, Id2, Vcam1) were significantly up-regulate …
Conditional transformation of mouse liver epithelial cells. An in vitro model for analysis of genetic events in hepatocarcinogenesis.
Lee GH, Ogawa K, Drinkwater NR. Lee GH, et al. Am J Pathol. 1995 Dec;147(6):1811-22. Am J Pathol. 1995. PMID: 7495305 Free PMC article.
In contrast, in the parental CHST10-2.1 cells, appreciable c-myc expression was observed at both temperatures. These results indicate that c-H-ras and c-myc can cooperate in complementing the ability of the temperature-sensitive large T antigen to immortalize mouse liver c …
In contrast, in the parental CHST10-2.1 cells, appreciable c-myc expression was observed at both temperatures. These results indicate …
Prognostic Values of EPDR1 Hypermethylation and Its Inhibitory Function on Tumor Invasion in Colorectal Cancer.
Chu CH, Chang SC, Wang HH, Yang SH, Lai KC, Lee TC. Chu CH, et al. Cancers (Basel). 2018 Oct 22;10(10):393. doi: 10.3390/cancers10100393. Cancers (Basel). 2018. PMID: 30360391 Free PMC article.
Based on quantitative methylation-specific polymerase chain reaction (Q-MSP), EGF, CHST10 and EPDR1 showed higher hypermethylated levels in CRC tissues than those in adjacent normal tissues, whereas BST2 showed hypomethylation in CRC tissues relative to adjacent normal tis …
Based on quantitative methylation-specific polymerase chain reaction (Q-MSP), EGF, CHST10 and EPDR1 showed higher hypermethylated lev …
Identification of novel hypermethylated genes and demethylating effect of vincristine in colorectal cancer.
Moon JW, Lee SK, Lee JO, Kim N, Lee YW, Kim SJ, Kang HJ, Kim J, Kim HS, Park SH. Moon JW, et al. J Exp Clin Cancer Res. 2014 Jan 6;33(1):4. doi: 10.1186/1756-9966-33-4. J Exp Clin Cancer Res. 2014. PMID: 24393480 Free PMC article.
Vincristine induced demethylation of methylated genes in CRC cells to the same extent as 5-aza-dC. The mRNA expression of AKR1B1, CHST10, ELOVL4, FLI1, SOX5, STK33, and ZNF304 was restored by treatment with 5-aza-dC and vincristine. CONCLUSION: These results suggest that t …
Vincristine induced demethylation of methylated genes in CRC cells to the same extent as 5-aza-dC. The mRNA expression of AKR1B1, CHST10 …
38 results