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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1971 1
1973 1
1974 2
1990 2
1991 1
1992 1
1993 3
1994 3
1995 2
1996 1
1997 5
1998 4
1999 5
2000 4
2001 8
2002 5
2003 3
2004 4
2005 3
2006 3
2007 5
2008 5
2009 10
2010 5
2011 10
2012 12
2013 11
2014 8
2015 10
2016 12
2017 8
2018 9
2019 5
2020 14
2021 2
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177 results
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Page 1
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández-Mateos J, Khan K, Lampis A, Eason K, Huntingford I, Burke R, Rata M, Koh DM, Tunariu N, Collins D, Hulkki-Wilson S, Ragulan C, Spiteri I, Moorcraft SY, Chau I, Rao S, Watkins D, Fotiadis N, Bali M, Darvish-Damavandi M, Lote H, Eltahir Z, Smyth EC, Begum R, Clarke PA, Hahne JC, Dowsett M, de Bono J, Workman P, Sadanandam A, Fassan M, Sansom OJ, Eccles S, Starling N, Braconi C, Sottoriva A, Robinson SP, Cunningham D, Valeri N. Vlachogiannis G, et al. Among authors: clarke pa. Science. 2018 Feb 23;359(6378):920-926. doi: 10.1126/science.aao2774. Science. 2018. PMID: 29472484 Free PMC article.
Small-molecule targeting of brachyury transcription factor addiction in chordoma.
Sharifnia T, Wawer MJ, Chen T, Huang QY, Weir BA, Sizemore A, Lawlor MA, Goodale A, Cowley GS, Vazquez F, Ott CJ, Francis JM, Sassi S, Cogswell P, Sheppard HE, Zhang T, Gray NS, Clarke PA, Blagg J, Workman P, Sommer J, Hornicek F, Root DE, Hahn WC, Bradner JE, Wong KK, Clemons PA, Lin CY, Kotz JD, Schreiber SL. Sharifnia T, et al. Among authors: clarke pa. Nat Med. 2019 Feb;25(2):292-300. doi: 10.1038/s41591-018-0312-3. Epub 2019 Jan 21. Nat Med. 2019. PMID: 30664779 Free PMC article.
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma.
Poon E, Liang T, Jamin Y, Walz S, Kwok C, Hakkert A, Barker K, Urban Z, Thway K, Zeid R, Hallsworth A, Box G, Ebus ME, Licciardello MP, Sbirkov Y, Lazaro G, Calton E, Costa BM, Valenti M, De Haven Brandon A, Webber H, Tardif N, Almeida GS, Christova R, Boysen G, Richards MW, Barone G, Ford A, Bayliss R, Clarke PA, De Bono J, Gray NS, Blagg J, Robinson SP, Eccles SA, Zheleva D, Bradner JE, Molenaar J, Vivanco I, Eilers M, Workman P, Lin CY, Chesler L. Poon E, et al. Among authors: clarke pa. J Clin Invest. 2020 Nov 2;130(11):5875-5892. doi: 10.1172/JCI134132. J Clin Invest. 2020. PMID: 33016930 Free PMC article.
The kinase polypharmacology landscape of clinical PARP inhibitors.
Antolin AA, Ameratunga M, Banerji U, Clarke PA, Workman P, Al-Lazikani B. Antolin AA, et al. Among authors: clarke pa. Sci Rep. 2020 Feb 17;10(1):2585. doi: 10.1038/s41598-020-59074-4. Sci Rep. 2020. PMID: 32066817 Free PMC article.
Inhibitors of cyclin-dependent kinases as cancer therapeutics.
Whittaker SR, Mallinger A, Workman P, Clarke PA. Whittaker SR, et al. Among authors: clarke pa. Pharmacol Ther. 2017 May;173:83-105. doi: 10.1016/j.pharmthera.2017.02.008. Epub 2017 Feb 5. Pharmacol Ther. 2017. PMID: 28174091 Free PMC article. Review.
Synthesis of highly substituted 2-spiropiperidines.
Griggs SD, Thompson N, Tape DT, Fabre M, Clarke PA. Griggs SD, et al. Among authors: clarke pa. Org Biomol Chem. 2018 Sep 19;16(36):6663-6674. doi: 10.1039/c8ob01272e. Org Biomol Chem. 2018. PMID: 30067258
177 results
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