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Editorial: Sigma Receptors.

Aydar E, Cobos EJ, Maurice T, Murell-Lagnado RD, Safrany ST. Aydar E, et al. Among authors: cobos ej. Front Pharmacol. 2020 Aug 27;11:590519. doi: 10.3389/fphar.2020.590519. eCollection 2020. Front Pharmacol. 2020. PMID: 33013426 Free PMC article. No abstract available.

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Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury.

Bravo-Caparrós I, Ruiz-Cantero MC, Perazzoli G, Cronin SJF, Vela JM, Hamed MF, Penninger JM, Baeyens JM, Cobos EJ, Nieto FR. Bravo-Caparrós I, et al. Among authors: cobos ej. FASEB J. 2020 Apr;34(4):5951-5966. doi: 10.1096/fj.201901921R. Epub 2020 Mar 10. FASEB J. 2020. PMID: 32157739

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Sigma-1 receptor and inflammatory pain.

Gris G, Cobos EJ, Zamanillo D, Portillo-Salido E. Gris G, et al. Among authors: cobos ej. Inflamm Res. 2015 Jun;64(6):377-81. doi: 10.1007/s00011-015-0819-8. Epub 2015 Apr 23. Inflamm Res. 2015. PMID: 25902777 Review.

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Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists.

Pasquinucci L, Parenti C, Ruiz-Cantero MC, Georgoussi Z, Pallaki P, Cobos EJ, Amata E, Marrazzo A, Prezzavento O, Arena E, Dichiara M, Salerno L, Turnaturi R. Pasquinucci L, et al. Among authors: cobos ej. ACS Med Chem Lett. 2020 Jan 28;11(5):678-685. doi: 10.1021/acsmedchemlett.9b00549. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435370 Free PMC article.

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Sigma-1 Receptor Antagonists: A New Class of Neuromodulatory Analgesics.

Sánchez-Fernández C, Entrena JM, Baeyens JM, Cobos EJ. Sánchez-Fernández C, et al. Among authors: cobos ej. Adv Exp Med Biol. 2017;964:109-132. doi: 10.1007/978-3-319-50174-1_9. Adv Exp Med Biol. 2017. PMID: 28315268 Review.

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Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain.

Ruiz-Cantero MC, González-Cano R, Tejada MÁ, Santos-Caballero M, Perazzoli G, Nieto FR, Cobos EJ. Ruiz-Cantero MC, et al. Among authors: cobos ej. Pharmacol Res. 2021 Jan;163:105339. doi: 10.1016/j.phrs.2020.105339. Epub 2020 Dec 1. Pharmacol Res. 2021. PMID: 33276102 Free article. Review.

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The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?

González-Cano R, Montilla-García Á, Ruiz-Cantero MC, Bravo-Caparrós I, Tejada MÁ, Nieto FR, Cobos EJ. González-Cano R, et al. Among authors: cobos ej. Neurosci Biobehav Rev. 2020 Jun;113:238-261. doi: 10.1016/j.neubiorev.2020.03.004. Epub 2020 Mar 5. Neurosci Biobehav Rev. 2020. PMID: 32147529 Review.

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Tetrodotoxin (TTX) as a therapeutic agent for pain.

Nieto FR, Cobos EJ, Tejada MÁ, Sánchez-Fernández C, González-Cano R, Cendán CM. Nieto FR, et al. Among authors: cobos ej. Mar Drugs. 2012 Feb;10(2):281-305. doi: 10.3390/md10020281. Epub 2012 Jan 31. Mar Drugs. 2012. PMID: 22412801 Free PMC article. Review.

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Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue.

Cortés-Montero E, Rodríguez-Muñoz M, Ruiz-Cantero MDC, Cobos EJ, Sánchez-Blázquez P, Garzón-Niño J. Cortés-Montero E, et al. Among authors: cobos ej. Int J Mol Sci. 2020 Dec 28;22(1):229. doi: 10.3390/ijms22010229. Int J Mol Sci. 2020. PMID: 33379368 Free PMC article.

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Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists.

Tejada MÁ, Montilla-García Á, González-Cano R, Bravo-Caparrós I, Ruiz-Cantero MC, Nieto FR, Cobos EJ. Tejada MÁ, et al. Among authors: cobos ej. Pharmacol Res. 2018 May;131:224-230. doi: 10.1016/j.phrs.2018.02.008. Epub 2018 Feb 15. Pharmacol Res. 2018. PMID: 29454675 Review.

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