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PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice.
Rodriguez LR, Tang SY, Roque Barboza W, Murthy A, Tomer Y, Cai TQ, Iyer S, Chavez K, Das US, Ghosh S, Cooper CH, Dimopoulos TT, Babu A, Connelly C, FitzGerald GA, Beers MF. Rodriguez LR, et al. Among authors: cooper ch. JCI Insight. 2023 Dec 22;8(24):e172977. doi: 10.1172/jci.insight.172977. JCI Insight. 2023. PMID: 37934604 Free PMC article.
Impaired AMPK control of alveolar epithelial cell metabolism promotes pulmonary fibrosis.
Rodríguez LR, Alysandratos KD, Katzen J, Murthy A, Roque Barboza W, Tomer Y, Bui S, Acín-Pérez R, Petcherski A, Minakin K, Carson P, Iyer S, Chavez K, Cooper CH, Babu A, Weiner AI, Vaughan AE, Arany Z, Shirihai OS, Kotton DN, Beers MF. Rodríguez LR, et al. Among authors: cooper ch. JCI Insight. 2025 Jul 1;10(15):e182578. doi: 10.1172/jci.insight.182578. eCollection 2025 Aug 8. JCI Insight. 2025. PMID: 40591409 Free PMC article.
Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis.
Rodriguez LR, Alysandratos KD, Katzen J, Murthy A, Barboza WR, Tomer Y, Acin-Perez R, Petcherski A, Minakin K, Carson P, Iyer S, Chavez K, Cooper CH, Babu A, Weiner AI, Vaughan AE, Arany Z, Shirihai OS, Kotton DN, Beers MF. Rodriguez LR, et al. Among authors: cooper ch. bioRxiv [Preprint]. 2024 Mar 28:2024.03.26.586649. doi: 10.1101/2024.03.26.586649. bioRxiv. 2024. Update in: JCI Insight. 2025 Jul 1;10(15):e182578. doi: 10.1172/jci.insight.182578. PMID: 38585863 Free PMC article. Updated. Preprint.
Aberrant intermediate alveolar epithelial cells promote pathogenic activation of lung fibroblasts in preclinical fibrosis models.
Hoffman ET, Shah A, Barboza WR, Rodriguez LR, Dherwani R, Dooley PE, Minakin K, Tomer Y, Ayers LJ, Jones D, Murthy A, Bennett A, Lange AN, Bawa PS, Wang F, Babu A, Chavez K, Nakamoto RS, Cooper CH, Basil MC, Raredon MSB, Kotton DN, Alysandratos KD, Katzen J. Hoffman ET, et al. Among authors: cooper ch. Nat Commun. 2025 Sep 30;16(1):8710. doi: 10.1038/s41467-025-63735-1. Nat Commun. 2025. PMID: 41027873 Free PMC article.
11 results