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Year Number of Results
2015 2
2016 4
2017 3
2018 1
2021 1
2022 0
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Page 1
Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol.
Harikumar KG, Coudrat T, Desai AJ, Dong M, Dengler DG, Furness SGB, Christopoulos A, Wootten D, Sergienko EA, Sexton PM, Miller LJ. Harikumar KG, et al. Among authors: coudrat t. Front Endocrinol (Lausanne). 2021 Dec 7;12:789957. doi: 10.3389/fendo.2021.789957. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34950108 Free PMC article.
Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM. Liang YL, et al. Among authors: coudrat t. Nature. 2017 Jun 1;546(7656):118-123. doi: 10.1038/nature22327. Epub 2017 Apr 24. Nature. 2017. PMID: 28437792 Free PMC article.
The role of kinetic context in apparent biased agonism at GPCRs.
Klein Herenbrink C, Sykes DA, Donthamsetti P, Canals M, Coudrat T, Shonberg J, Scammells PJ, Capuano B, Sexton PM, Charlton SJ, Javitch JA, Christopoulos A, Lane JR. Klein Herenbrink C, et al. Among authors: coudrat t. Nat Commun. 2016 Feb 24;7:10842. doi: 10.1038/ncomms10842. Nat Commun. 2016. PMID: 26905976 Free PMC article.
A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures.
Wootten D, Reynolds CA, Koole C, Smith KJ, Mobarec JC, Simms J, Quon T, Coudrat T, Furness SG, Miller LJ, Christopoulos A, Sexton PM. Wootten D, et al. Among authors: coudrat t. Mol Pharmacol. 2016 Mar;89(3):335-47. doi: 10.1124/mol.115.101246. Epub 2015 Dec 23. Mol Pharmacol. 2016. PMID: 26700562 Free PMC article.