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62 results

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Page 1
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases.
Craig RA 2nd, De Vicente J, Estrada AA, Feng JA, Lexa KW, Canet MJ, Dowdle WE, Erickson RI, Flores BN, Haddick PCG, Kane LA, Lewcock JW, Moerke NJ, Poda SB, Sweeney Z, Takahashi RH, Tong V, Wang J, Yulyaningsih E, Solanoy H, Scearce-Levie K, Sanchez PE, Tang L, Xu M, Zhang R, Osipov M. Craig RA 2nd, et al. J Med Chem. 2024 Apr 11;67(7):5758-5782. doi: 10.1021/acs.jmedchem.3c02422. Epub 2024 Mar 21. J Med Chem. 2024. PMID: 38511649
Preparation of 1,5-Dioxaspiro[5.5]undecan-3-one.
Craig RA 2nd, Smith RC, Pritchett BP, Estipona BI, Stoltz BM. Craig RA 2nd, et al. Organic Synth. 2016;93:210-227. doi: 10.15227/orgsyn.093.0210. Organic Synth. 2016. PMID: 28729749 Free PMC article.
Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis.
Craig RA 2nd, Fox BM, Hu C, Lexa KW, Osipov M, Thottumkara AP, Larhammar M, Miyamoto T, Rana A, Kane LA, Yulyaningsih E, Solanoy H, Nguyen H, Chau R, Earr T, Kajiwara Y, Fleck D, Lucas A, Haddick PCG, Takahashi RH, Tong V, Wang J, Canet MJ, Poda SB, Scearce-Levie K, Srivastava A, Sweeney ZK, Xu M, Zhang R, He J, Lei Y, Zhuo Z, de Vicente J. Craig RA 2nd, et al. J Med Chem. 2022 Dec 22;65(24):16290-16312. doi: 10.1021/acs.jmedchem.2c01056. Epub 2022 Dec 5. J Med Chem. 2022. PMID: 36469401
Catalytic enantioselective total synthesis of (+)-eucomic acid.
Estipona BI, Pritchett BP, Craig RA 2nd, Stoltz BM. Estipona BI, et al. Among authors: craig ra 2nd. Tetrahedron. 2016 Jun 30;72(26):3707-3712. doi: 10.1016/j.tet.2016.02.059. Epub 2016 Mar 2. Tetrahedron. 2016. PMID: 27546916 Free PMC article.
62 results