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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 1
1996 1
1997 4
1998 7
1999 5
2000 7
2001 7
2002 10
2003 9
2004 23
2005 26
2006 28
2007 32
2008 31
2009 29
2010 57
2011 46
2012 44
2013 48
2014 36
2015 36
2016 35
2017 27
2018 26
2019 24
2020 22
2021 30
2022 16
2023 16
2024 7

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599 results

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Page 1
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells.
Vinogradova EV, Zhang X, Remillard D, Lazar DC, Suciu RM, Wang Y, Bianco G, Yamashita Y, Crowley VM, Schafroth MA, Yokoyama M, Konrad DB, Lum KM, Simon GM, Kemper EK, Lazear MR, Yin S, Blewett MM, Dix MM, Nguyen N, Shokhirev MN, Chin EN, Lairson LL, Melillo B, Schreiber SL, Forli S, Teijaro JR, Cravatt BF. Vinogradova EV, et al. Among authors: cravatt bf. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29. Cell. 2020. PMID: 32730809 Free PMC article.
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, Li H, Germain J, Barbas S, Vaughan J, Hanigan TW, Vartabedian VF, Reinhardt CJ, Dix MM, Koo SJ, Heo I, Teijaro JR, Simon GM, Ghosh B, Abdel-Wahab O, Ahn K, Saghatelian A, Melillo B, Schreiber SL, Yeo GW, Cravatt BF. Lazear MR, et al. Among authors: cravatt bf. Mol Cell. 2023 May 18;83(10):1725-1742.e12. doi: 10.1016/j.molcel.2023.03.026. Epub 2023 Apr 20. Mol Cell. 2023. PMID: 37084731
Proteome-wide covalent ligand discovery in native biological systems.
Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF. Backus KM, et al. Among authors: cravatt bf. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15. Nature. 2016. PMID: 27309814 Free PMC article.
Remodeling oncogenic transcriptomes by small molecules targeting NONO.
Kathman SG, Koo SJ, Lindsey GL, Her HL, Blue SM, Li H, Jaensch S, Remsberg JR, Ahn K, Yeo GW, Ghosh B, Cravatt BF. Kathman SG, et al. Among authors: cravatt bf. Nat Chem Biol. 2023 Jul;19(7):825-836. doi: 10.1038/s41589-023-01270-0. Epub 2023 Mar 2. Nat Chem Biol. 2023. PMID: 36864190 Free PMC article.
In situ identification of cellular drug targets in mammalian tissue.
Pang Z, Schafroth MA, Ogasawara D, Wang Y, Nudell V, Lal NK, Yang D, Wang K, Herbst DM, Ha J, Guijas C, Blankman JL, Cravatt BF, Ye L. Pang Z, et al. Among authors: cravatt bf. Cell. 2022 May 12;185(10):1793-1805.e17. doi: 10.1016/j.cell.2022.03.040. Epub 2022 Apr 27. Cell. 2022. PMID: 35483372 Free PMC article.
Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine.
Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AJ, Rodriguez JL, Rodiles S, Masuda K, Teijaro JR, Simon GM, Patricelli MP, Cravatt BF. Kavanagh ME, et al. Among authors: cravatt bf. Nat Chem Biol. 2022 Dec;18(12):1388-1398. doi: 10.1038/s41589-022-01098-0. Epub 2022 Sep 12. Nat Chem Biol. 2022. PMID: 36097295 Free PMC article.
599 results