Cretton EM[au] - Search Results

Year	Number of Results
1990	1
1991	3
1992	3
1993	3
1995	1
2023	0

1

In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.

Cretton EM, Zhou Z, Kidd LB, McClure HM, Kaul S, Hitchcock MJ, Sommadossi JP. Cretton EM, et al. Antimicrob Agents Chemother. 1993 Sep;37(9):1816-25. doi: 10.1128/AAC.37.9.1816. Antimicrob Agents Chemother. 1993. PMID: 8239589 Free PMC article.

2

Clinical pharmacokinetics of 3'-azido-3'-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3'-amino-3'-deoxythymidine.

Stagg MP, Cretton EM, Kidd L, Diasio RB, Sommadossi JP. Stagg MP, et al. Among authors: cretton em. Clin Pharmacol Ther. 1992 Jun;51(6):668-76. doi: 10.1038/clpt.1992.79. Clin Pharmacol Ther. 1992. PMID: 1611806 Clinical Trial.

3

Reduction of 3'-azido-3'-deoxythymidine to 3'-amino-3'-deoxythymidine in human liver microsomes and its relationship to cytochrome P450.

Placidi L, Cretton EM, Placidi M, Sommadossi JP. Placidi L, et al. Among authors: cretton em. Clin Pharmacol Ther. 1993 Aug;54(2):168-76. doi: 10.1038/clpt.1993.128. Clin Pharmacol Ther. 1993. PMID: 8354026

4

Effects of 5-benzylacyclouridine, an inhibitor of uridine phosphorylase, on the pharmacokinetics of uridine in rhesus monkeys: implications for chemotherapy.

Sommadossi JP, Cretton EM, Kidd LB, McClure HM, Anderson DC, el Kouni MH. Sommadossi JP, et al. Among authors: cretton em. Cancer Chemother Pharmacol. 1995;37(1-2):14-22. doi: 10.1007/BF00685624. Cancer Chemother Pharmacol. 1995. PMID: 7497584

5

Glucuronidation of 3'-azido-3'-deoxythymidine by rat and human liver microsomes.

Cretton EM, Waterhous DV, Bevan R, Sommadossi JP. Cretton EM, et al. Drug Metab Dispos. 1990 May-Jun;18(3):369-72. Drug Metab Dispos. 1990. PMID: 1974201

6

Pharmacokinetics of 3'-azido-3'-deoxythymidine and its catabolites and interactions with probenecid in rhesus monkeys.

Cretton EM, Schinazi RF, McClure HM, Anderson DC, Sommadossi JP. Cretton EM, et al. Antimicrob Agents Chemother. 1991 May;35(5):801-7. doi: 10.1128/AAC.35.5.801. Antimicrob Agents Chemother. 1991. PMID: 1854160 Free PMC article.

7

Reduction of 3'-azido-2',3'-dideoxynucleosides to their 3'-amino metabolite is mediated by cytochrome P-450 and NADPH-cytochrome P-450 reductase in rat liver microsomes.

Cretton EM, Sommadossi JP. Cretton EM, et al. Drug Metab Dispos. 1993 Sep-Oct;21(5):946-50. Drug Metab Dispos. 1993. PMID: 7902260

8

Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.

Cretton EM, Xie MY, Bevan RJ, Goudgaon NM, Schinazi RF, Sommadossi JP. Cretton EM, et al. Mol Pharmacol. 1991 Feb;39(2):258-66. Mol Pharmacol. 1991. PMID: 1996084

9

Modulation of 3'-azido-3'-deoxythymidine catabolism by probenecid and acetaminophen in freshly isolated rat hepatocytes.

Cretton EM, Sommadossi JP. Cretton EM, et al. Biochem Pharmacol. 1991 Sep 12;42(7):1475-80. doi: 10.1016/0006-2952(91)90461-d. Biochem Pharmacol. 1991. PMID: 1930271

10

Comparative effects of 3'-azido-3'-deoxythymidine and its metabolite 3'-amino-3'-deoxythymidine on hemoglobin synthesis in K-562 human leukemia cells.

Weidner DA, Bridges EG, Cretton EM, Sommadossi JP. Weidner DA, et al. Among authors: cretton em. Mol Pharmacol. 1992 Feb;41(2):252-8. Mol Pharmacol. 1992. PMID: 1538705

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