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COVID-19 and Hyperimmune sera: A feasible plan B to fight against coronavirus.
da Costa CBP, Martins FJ, da Cunha LER, Ratcliffe NA, Cisne de Paula R, Castro HC. da Costa CBP, et al. Among authors: da cunha ler. Int Immunopharmacol. 2021 Jan;90:107220. doi: 10.1016/j.intimp.2020.107220. Epub 2020 Nov 20. Int Immunopharmacol. 2021. PMID: 33302034 Free PMC article. Review.
Using in vivo animal models for studying SARS-CoV-2.
Da Costa CBP, Cruz ACM, Penha JCQ, Castro HC, Da Cunha LER, Ratcliffe NA, Cisne R, Martins FJ. Da Costa CBP, et al. Among authors: da cunha ler. Expert Opin Drug Discov. 2022 Feb;17(2):121-137. doi: 10.1080/17460441.2022.1995352. Epub 2021 Nov 3. Expert Opin Drug Discov. 2022. PMID: 34727803 Free PMC article.
Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency.
Cunha LER, Stolet AA, Strauch MA, Pereira VAR, Dumard CH, Gomes AMO, Monteiro FL, Higa LM, Souza PNC, Fonseca JG, Pontes FE, Meirelles LGR, Albuquerque JWM, Sacramento CQ, Fintelman-Rodrigues N, Lima TM, Alvim RGF, Marsili FF, Caldeira MM, Zingali RB, de Oliveira GAP, Souza TML, Silva AS, Muller R, Rodrigues DDRF, Jesus da Costa L, Alves ADR, Pinto MA, Oliveira AC, Guedes HLM, Tanuri A, Castilho LR, Silva JL. Cunha LER, et al. iScience. 2021 Nov 19;24(11):103315. doi: 10.1016/j.isci.2021.103315. Epub 2021 Oct 23. iScience. 2021. PMID: 34723156 Free PMC article.
Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.
Barbosa AN, Ferreira RS Jr, de Carvalho FCT, Schuelter-Trevisol F, Mendes MB, Mendonça BC, Batista JN, Trevisol DJ, Boyer L, Chippaux JP, Medolago NB, Cassaro CV, Carneiro MTR, de Oliveira APP, Pimenta DC, da Cunha LER, Dos Santos LD, Barraviera B. Barbosa AN, et al. Among authors: da cunha ler. Front Immunol. 2021 Mar 23;12:653151. doi: 10.3389/fimmu.2021.653151. eCollection 2021. Front Immunol. 2021. PMID: 33841437 Free PMC article. Clinical Trial.