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Page 1
Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers.
Gipson GR, Nolan K, Kattamuri C, Kenny AP, Agricola Z, Edwards NA, Zinski J, Czepnik M, Mullins MC, Zorn AM, Thompson TB. Gipson GR, et al. Among authors: czepnik m. BMC Biol. 2023 Feb 1;21(1):16. doi: 10.1186/s12915-023-01522-4. BMC Biol. 2023. PMID: 36726183 Free PMC article.
Molecular characterization of latent GDF8 reveals mechanisms of activation.
Walker RG, McCoy JC, Czepnik M, Mills MJ, Hagg A, Walton KL, Cotton TR, Hyvönen M, Lee RT, Gregorevic P, Harrison CA, Thompson TB. Walker RG, et al. Among authors: czepnik m. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E866-E875. doi: 10.1073/pnas.1714622115. Epub 2018 Jan 18. Proc Natl Acad Sci U S A. 2018. PMID: 29348202 Free PMC article.
Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors.
Goebel EJ, Kattamuri C, Gipson GR, Krishnan L, Chavez M, Czepnik M, Maguire MC, Grenha R, Håkansson M, Logan DT, Grinberg AV, Sako D, Castonguay R, Kumar R, Thompson TB. Goebel EJ, et al. Among authors: czepnik m. iScience. 2021 Dec 9;25(1):103590. doi: 10.1016/j.isci.2021.103590. eCollection 2022 Jan 21. iScience. 2021. PMID: 35005539 Free PMC article.
Structural basis for potency differences between GDF8 and GDF11.
Walker RG, Czepnik M, Goebel EJ, McCoy JC, Vujic A, Cho M, Oh J, Aykul S, Walton KL, Schang G, Bernard DJ, Hinck AP, Harrison CA, Martinez-Hackert E, Wagers AJ, Lee RT, Thompson TB. Walker RG, et al. Among authors: czepnik m. BMC Biol. 2017 Mar 3;15(1):19. doi: 10.1186/s12915-017-0350-1. BMC Biol. 2017. PMID: 28257634 Free PMC article.
Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Goebel EJ, Corpina RA, Hinck CS, Czepnik M, Castonguay R, Grenha R, Boisvert A, Miklossy G, Fullerton PT, Matzuk MM, Idone VJ, Economides AN, Kumar R, Hinck AP, Thompson TB. Goebel EJ, et al. Among authors: czepnik m. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15505-15513. doi: 10.1073/pnas.1906253116. Epub 2019 Jul 17. Proc Natl Acad Sci U S A. 2019. PMID: 31315975 Free PMC article.