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Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy.
Imre G, Takács B, Czipa E, Drubi AB, Jaksa G, Latinovics D, Nagy A, Karkas R, Hudoba L, Vásárhelyi BM, Pankotai-Bodó G, Blastyák A, Hegedűs Z, Germán P, Bálint B, Ahmed Abdullah KS, Kopasz AG, Kovács A, Nagy LG, Sükösd F, Pintér L, Rülicke T, Barta E, Nagy I, Haracska L, Mátés L. Imre G, et al. Among authors: czipa e. Mol Ther Methods Clin Dev. 2023 Mar 14;29:145-159. doi: 10.1016/j.omtm.2023.03.003. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 37025950 Free PMC article.
PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology.
Simandi Z, Czipa E, Horvath A, Koszeghy A, Bordas C, Póliska S, Juhász I, Imre L, Szabó G, Dezso B, Barta E, Sauer S, Karolyi K, Kovacs I, Hutóczki G, Bognár L, Klekner Á, Szucs P, Bálint BL, Nagy L. Simandi Z, et al. Among authors: czipa e. Stem Cells. 2015 Mar;33(3):726-41. doi: 10.1002/stem.1894. Stem Cells. 2015. PMID: 25388207 Free article.