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Showing results for d h hathaway
Search for D E Hathway instead (1 results)
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F.
Ivanchenko MV, Hathaway DM, Klein AJ, Pan B, Strelkova O, De-la-Torre P, Wu X, Peters CW, Mulhall EM, Booth KT, Goldstein C, Brower J, Sotomayor M, Indzhykulian AA, Corey DP. Ivanchenko MV, et al. Nat Commun. 2023 Apr 26;14(1):2400. doi: 10.1038/s41467-023-38038-y. Nat Commun. 2023. PMID: 37100771 Free PMC article.
Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice.
Sun B, Rouzbehani OMT, Kramer RJ, Ghosh R, Perelli RM, Atkins S, Fatahian AN, Davis K, Szulik MW, Goodman MA, Hathaway MA, Chi E, Word TA, Tunuguntla H, Denfield SW, Wehrens XHT, Whitehead KJ, Abdelnasser HY, Warren JS, Wu M, Franklin S, Boudina S, Landstrom AP. Sun B, et al. Circ Heart Fail. 2023 Dec;16(12):e010351. doi: 10.1161/CIRCHEARTFAILURE.122.010351. Epub 2023 Dec 19. Circ Heart Fail. 2023. PMID: 38113297 Free PMC article.
Chemical Epigenetic Regulation of Adeno-Associated Virus Delivered Transgenes.
Umaña JD, Wasserman SR, Song L, Goel AA, Yu X, Jin J, Hathaway NA. Umaña JD, et al. Hum Gene Ther. 2023 Sep;34(17-18):947-957. doi: 10.1089/hum.2023.005. Hum Gene Ther. 2023. PMID: 37624737 Free PMC article.
The highest levels of transgene product activity are seen 24 h following CEM87 treatment. Additionally, the CEM87-mediated enhancement of different transgene products with either Luciferase or green fluorescent protein (GFP) was observed in multiple cell lines and enhancem …
The highest levels of transgene product activity are seen 24 h following CEM87 treatment. Additionally, the CEM87-mediated enhancemen …
Left Ventricular Segmental Strain Identifies Unique Myocardial Deformation Patterns After Intrinsic and Extrinsic Stressors in Mice.
Kunovac A, Hathaway QA, Burrage EN, Coblentz T, Kelley EE, Sengupta PP, Hollander JM, Chantler PD. Kunovac A, et al. Ultrasound Med Biol. 2022 Oct;48(10):2128-2138. doi: 10.1016/j.ultrasmedbio.2022.06.004. Epub 2022 Aug 4. Ultrasound Med Biol. 2022. PMID: 35933241 Free PMC article.
At 18 wk, lean and obese mice were further randomized into UCMS and non-UCMS groups (UCMS, 7 h/d, 5 d/wk, for 8 wk). Echocardiography was performed at baseline (6 wk), post-HFD (18 wk) and post-UCMS (26 wk). ...
At 18 wk, lean and obese mice were further randomized into UCMS and non-UCMS groups (UCMS, 7 h/d, 5 d/wk, for 8 wk). Ec …
Introduction of D-phenylalanine enhanced the receptor binding affinities of gonadotropin-releasing hormone peptides.
Lu J, Hathaway HJ, Royce ME, Prossnitz ER, Miao Y. Lu J, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):725-30. doi: 10.1016/j.bmcl.2013.12.120. Epub 2014 Jan 6. Bioorg Med Chem Lett. 2014. PMID: 24418777 Free PMC article.
Building upon the construct of DOTA-Ahx-(D-Lys(6)-GnRH1) we previously reported, an aromatic amino acid of D-Phe was inserted either between the DOTA and Ahx or between the Ahx and D-Lys(6) to generate new DOTA-D-Phe-Ahx-(D-Lys(6)-GnRH) or DOTA- …
Building upon the construct of DOTA-Ahx-(D-Lys(6)-GnRH1) we previously reported, an aromatic amino acid of D-Phe was inserted …
Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides.
Guo H, Lu J, Hathaway H, Royce ME, Prossnitz ER, Miao Y. Guo H, et al. Bioconjug Chem. 2011 Aug 17;22(8):1682-9. doi: 10.1021/bc200252j. Epub 2011 Jul 20. Bioconjug Chem. 2011. PMID: 21749045 Free PMC article.
The IC(50) values of DOTA-Ahx-(D-Lys(6)-GnRH1), DOTA-Ahx-(D-Lys(6)-GnRH2) and DOTA-Ahx-(L-Lys(6)-GnRH3) were 36.1 nM, 10.6 mM and 4.3 mM, respectively. ...Furthermore, the biodistribution and tumor imaging properties of (111)In-DOTA-Ahx-(D-Lys(6)-GnRH1) were …
The IC(50) values of DOTA-Ahx-(D-Lys(6)-GnRH1), DOTA-Ahx-(D-Lys(6)-GnRH2) and DOTA-Ahx-(L-Lys(6)-GnRH3) were 36.1 nM, 10.6 mM …
84 results