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Did you mean d khabbazzadeh (1 results)?
Characteristics and Lethality of a Novel Recombinant Dermonecrotic Venom Phospholipase D from Hemiscorpius lepturus.
Torabi E, Behdani M, Chafi MH, Moazzami R, Sabatier JM, Khalaj V, Shahbazzadeh D, Bagheri KP. Torabi E, et al. Toxins (Basel). 2017 Mar 13;9(3):102. doi: 10.3390/toxins9030102. Toxins (Basel). 2017. PMID: 28335389 Free PMC article.
The lethality and toxicity of brown spiders' venom have been attributed to its phospholipase D activity. This study aims to identify a phospholipase D with possible lethality and dermonecrotic activity in H. lepturus venom. ...In conclusion, Hl-RecPLD1 is a highly a …
The lethality and toxicity of brown spiders' venom have been attributed to its phospholipase D activity. This study aims to identify …
Cellular Immunity in Mice Vaccinated with Recombinant Phospholipase D Toxoid of Hemiscorpius lepturus Scorpion.
Safari-Foroushani N, Modarressi MH, Pooshang Bagheri K, Behdani M, Shahbazzadeh D. Safari-Foroushani N, et al. J Arthropod Borne Dis. 2022 Mar 31;16(1):1-12. doi: 10.18502/jad.v16i1.11187. eCollection 2022 Mar. J Arthropod Borne Dis. 2022. PMID: 36636239 Free PMC article.
Numerous studies have been conducted on phospholipases, especially phospholipase D, in this scorpion's venom, and the results have shown this protein to be the main cause of death. ...
Numerous studies have been conducted on phospholipases, especially phospholipase D, in this scorpion's venom, and the results have sh …
Novel Mutant Phospholipase D from Hemiscorpius lepturus Acts as A Highly Immunogen in BALB/c Mice Against the Lethality of Scorpion Venom.
Soleimani Moez A, H Sajedi R, Pooshang Bagheri K, Sabatier JM, Shahbazzadeh D. Soleimani Moez A, et al. Molecules. 2020 Apr 4;25(7):1673. doi: 10.3390/molecules25071673. Molecules. 2020. PMID: 32260428 Free PMC article.
In our previous studies during the last decade, we demonstrated that the medical complications are attributable to the presence of phospholipase D (PLD) as a major toxin in the venom. With the purpose of designing and constructing a vaccine against H. lepturus for humans, …
In our previous studies during the last decade, we demonstrated that the medical complications are attributable to the presence of phospholi …
Antigenic and Substrate Preference Differences between Scorpion and Spider Dermonecrotic Toxins, a Comparative Investigation.
Ben Yekhlef R, Felicori L, Santos LH, F B Oliveira C, Fadhloun R, Torabi E, Shahbazzadeh D, Pooshang Bagheri K, Salgado Ferreira R, Borchani L. Ben Yekhlef R, et al. Toxins (Basel). 2020 Oct 1;12(10):631. doi: 10.3390/toxins12100631. Toxins (Basel). 2020. PMID: 33019554 Free PMC article.
To better understand the properties of these toxins, we designed a study to compare recombinant Heminecrolysin (rHNC) and rLiD1, the major phospholipase D toxins of scorpion and spider venom, respectively. Using a competitive ELISA and a hemolytic inhibition test, we come …
To better understand the properties of these toxins, we designed a study to compare recombinant Heminecrolysin (rHNC) and rLiD1, the major p …
The pathological effects of Heminecrolysin, a dermonecrotic toxin from Hemiscorpius lepturus scorpion venom are mediated through its lysophospholipase D activity.
Borchani L, Sassi A, Ben Gharsa H, Safra I, Shahbazzadeh D, Ben Lasfar Z, El Ayeb M. Borchani L, et al. Toxicon. 2013 Jun;68:30-9. doi: 10.1016/j.toxicon.2013.03.012. Epub 2013 Apr 2. Toxicon. 2013. PMID: 23562369
We have previously identified Heminecrolysin, a sphingomyelinase D (SMaseD), as the major protein responsible for the main pathological effects observed following Hemiscorpius (H.) lepturus scorpion envenomation. ...We show that Heminecrolysin highly hydrolyzes lysophospha …
We have previously identified Heminecrolysin, a sphingomyelinase D (SMaseD), as the major protein responsible for the main pathologic …
Innovative production of highly potent equine neutralizing antibody against Hemiscorpius lepturus scorpion venom using recombinant mPLD1 protein.
Amirkhani A, Karami-Mohajeri S, Heidari MR, Amirheidari B, Mandegary A, Hosseininejad-Chafi M, Khalili-Salmasi M, Tavangarroosta S, Pooshang Bagheri K, Shahbazzadeh D. Amirkhani A, et al. Toxicon. 2025 Feb;255:108260. doi: 10.1016/j.toxicon.2025.108260. Epub 2025 Jan 20. Toxicon. 2025. PMID: 39842515
The venom's major toxin, which includes phospholipase D (PLD), is responsible for various systemic complications. In prior studies, we identified a native phospholipase D (PLD) toxin as a key lethal factor in the venom of H. lepturus. ...
The venom's major toxin, which includes phospholipase D (PLD), is responsible for various systemic complications. In prior studies, w …
Heminecrolysin, the first hemolytic dermonecrotic toxin purified from scorpion venom.
Borchani L, Sassi A, Shahbazzadeh D, Strub JM, Tounsi-Guetteti H, Boubaker MS, Akbari A, Van Dorsselaer A, El Ayeb M. Borchani L, et al. Toxicon. 2011 Jul;58(1):130-9. doi: 10.1016/j.toxicon.2011.05.016. Epub 2011 May 31. Toxicon. 2011. PMID: 21658401
Tryptic digestion and MS/MS analysis of obtained peptides showed homology with previously described brown spider sphingomyelinases D. Functional characterization of Heminecrolysin indicated a sphingomyelinase D, a complement-dependent hemolysis properties and a derm …
Tryptic digestion and MS/MS analysis of obtained peptides showed homology with previously described brown spider sphingomyelinases D. …
Developing recombinant phospholipase D1 (rPLD1) toxoid from Iranian Hemiscorpius lepturus scorpion and its protective effects in BALB/c mice.
Safari Foroushani N, Modarressi MH, Behdani M, Torabi E, Pooshang Bagheri K, Shahbazzadeh D. Safari Foroushani N, et al. Toxicon. 2018 Sep 15;152:30-36. doi: 10.1016/j.toxicon.2018.07.003. Epub 2018 Jul 6. Toxicon. 2018. PMID: 29981815
The clinical signs of H. lepturus envenomation, including dermonecrosis, hematuria, renal failure and early death, are attributed to phospholipase D activity. This study was conducted to develop a novel recombinant phospholipase D1 (rPLD1) toxoid and investigate its immuno …
The clinical signs of H. lepturus envenomation, including dermonecrosis, hematuria, renal failure and early death, are attributed to phospho …
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