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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 2
1948 1
1955 1
1958 1
1959 1
1963 2
1964 2
1965 1
1966 1
1967 3
1968 6
1969 2
1970 3
1971 3
1972 4
1973 6
1974 3
1975 2
1976 10
1977 8
1978 6
1979 7
1980 10
1981 8
1982 9
1983 15
1984 21
1985 20
1986 15
1987 39
1988 37
1989 28
1990 47
1991 58
1992 60
1993 70
1994 62
1995 86
1996 98
1997 106
1998 117
1999 156
2000 136
2001 204
2002 241
2003 285
2004 339
2005 372
2006 449
2007 489
2008 512
2009 571
2010 656
2011 644
2012 737
2013 748
2014 1007
2015 1191
2016 1346
2017 1450
2018 1608
2019 1841
2020 2037
2021 2362
2022 2658
2023 2782
2024 3212
2025 1852

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27,657 results

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Page 1
The role of vitamin D in periodontal health and disease.
Lu EM. Lu EM. J Periodontal Res. 2023 Apr;58(2):213-224. doi: 10.1111/jre.13083. Epub 2022 Dec 20. J Periodontal Res. 2023. PMID: 36537578 Review.
Vitamin D plays an essential role in calcium and bone metabolism, immune regulation and possesses profound anti-inflammatory effects. ...This review aims to first examine the biological mechanisms by which vitamin D might influence the pathogenesis of periodontal di …
Vitamin D plays an essential role in calcium and bone metabolism, immune regulation and possesses profound anti-inflammatory effects. …
(177)Lu-Labeled DOTA-conjugated AE105 peptide (Asp-Cha-Phe-(d)Ser-(d)Arg-Tyr-Leu-Trp-Ser-CONH(2)).
Chopra A. Chopra A. 2012 Sep 13 [updated 2012 Nov 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Sep 13 [updated 2012 Nov 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23166959 Free Books & Documents. Review.
A radiolabeled linear peptide that has a high affinity for the uPAR, AE105 (Asp-Cha-Phe-(d)Ser-(d)Arg-Tyr-Leu-Trp-Ser-CONH(2)), is considered to be the most promising ligand for the detection and imaging of cancerous tissues that overexpress the uPAR (1). ...In an e …
A radiolabeled linear peptide that has a high affinity for the uPAR, AE105 (Asp-Cha-Phe-(d)Ser-(d)Arg-Tyr-Leu-Trp-Ser-CONH(2)) …
(177)Lu-DOTA-Tyr(3)-c(Cys-Tyr-Trp-Lys-Thr-Cys)-Thr-Lys(cypate)-NH(2).
Zhang H. Zhang H. 2008 Mar 20 [updated 2008 Apr 22]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Mar 20 [updated 2008 Apr 22]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641372 Free Books & Documents. Review.
For example, octreotide, a SST analog with a peptide sequence of eight amino acids (D-Phe-c(Cys-Tyr-D-Trp-Lys-Thr-Cys)-Thr(ol)), possesses a much higher affinity (~2 nM) binding to SSTR-2, -3, and -5 than binding to SSTR-1 and -4 (>1,000 nM). In addition to sympt …
For example, octreotide, a SST analog with a peptide sequence of eight amino acids (D-Phe-c(Cys-Tyr-D-Trp-Lys-Thr-Cys)-Thr(ol) …
Lu AF35700 reverses the phencyclidine-induced disruption of thalamo-cortical activity by blocking dopamine D(1) and D(2) receptors.
Riga MS, Paz V, Didriksen M, Celada P, Artigas F. Riga MS, et al. Eur J Pharmacol. 2023 Aug 15;953:175802. doi: 10.1016/j.ejphar.2023.175802. Epub 2023 Jun 7. Eur J Pharmacol. 2023. PMID: 37295763
Antipsychotic drugs of different chemical/pharmacological families show preferential dopamine (DA) D(2) receptor (D(2)-R) vs. D(1) receptor (D(1)-R) affinity, with the exception of clozapine, the gold standard of schizophrenia treatment, which shows a …
Antipsychotic drugs of different chemical/pharmacological families show preferential dopamine (DA) D(2) receptor (D(2)-R) vs. …
Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults.
Hibberd AA, Yde CC, Ziegler ML, Honoré AH, Saarinen MT, Lahtinen S, Stahl B, Jensen HM, Stenman LK. Hibberd AA, et al. Benef Microbes. 2019 Mar 13;10(2):121-135. doi: 10.3920/BM2018.0028. Epub 2018 Dec 10. Benef Microbes. 2019. PMID: 30525950 Clinical Trial.
Faecal and plasma samples were obtained from a protocol compliant subset (n=134) of participants from a larger clinical study where participants were randomised (1:1:1:1) into four groups: (1) placebo, 12 g/d microcrystalline cellulose; (2) Litesse Ultra polydextrose (L …
Faecal and plasma samples were obtained from a protocol compliant subset (n=134) of participants from a larger clinical study where particip …
Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults-Randomized Controlled Trial.
Stenman LK, Lehtinen MJ, Meland N, Christensen JE, Yeung N, Saarinen MT, Courtney M, Burcelin R, Lähdeaho ML, Linros J, Apter D, Scheinin M, Kloster Smerud H, Rissanen A, Lahtinen S. Stenman LK, et al. EBioMedicine. 2016 Nov;13:190-200. doi: 10.1016/j.ebiom.2016.10.036. Epub 2016 Oct 26. EBioMedicine. 2016. PMID: 27810310 Free PMC article. Clinical Trial.
We investigated the possible effects of Bifidobacterium animalisssp. lactis 420 (B420) and the dietary fiber Litesse Ultra polydextrose (LU) on body fat mass and other obesity-related parameters. METHODS: 225 healthy volunteers (healthy, BMI 28-34.9) were randomized into f …
We investigated the possible effects of Bifidobacterium animalisssp. lactis 420 (B420) and the dietary fiber Litesse Ultra polydextrose ( …
Cure of Disseminated Human Lymphoma with [(177)Lu]Lu-Ofatumumab in a Preclinical Model.
Shim K, Longtine MS, Abou DS, Hoegger MJ, Laforest RS, Thorek DLJ, Wahl RL. Shim K, et al. J Nucl Med. 2023 Apr;64(4):542-548. doi: 10.2967/jnumed.122.264816. Epub 2022 Nov 10. J Nucl Med. 2023. PMID: 36357179 Free PMC article.
In the therapy study, median survival of untreated mice was 19 d, not statistically different from mice treated with 8.51 MBq of [(177)Lu]Lu-IgG (25 d). Unlabeled ofatumumab increased survival to 46 d, similar to 0.74 MBq of [(177)Lu]L …
In the therapy study, median survival of untreated mice was 19 d, not statistically different from mice treated with 8.51 MBq of [(17 …
Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-α (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors.
Poplawski SE, Hallett RM, Dornan MH, Novakowski KE, Pan S, Belanger AP, Nguyen QD, Wu W, Felten AE, Liu Y, Ahn SH, Hergott VS, Jones B, Lai JH, McCann JAB, Bachovchin WW. Poplawski SE, et al. J Nucl Med. 2024 Jan 2;65(1):100-108. doi: 10.2967/jnumed.123.266345. J Nucl Med. 2024. PMID: 38050111 Free article.
One such pharmacophore is the boronic acid derivative N-(pyridine-4-carbonyl)-d-Ala-boroPro, a potent and selective FAP inhibitor (FAPI). In this study, the diagnostic and therapeutic (theranostic) potential of N-(pyridine-4-carbonyl)-d-Ala-boroPro-based metal-chela …
One such pharmacophore is the boronic acid derivative N-(pyridine-4-carbonyl)-d-Ala-boroPro, a potent and selective FAP inhibitor (FA …
Fibroblast activation protein targeted radiotherapy induces an immunogenic tumor microenvironment and enhances the efficacy of PD-1 immune checkpoint inhibition.
Zboralski D, Osterkamp F, Christensen E, Bredenbeck A, Schumann A, Hoehne A, Schneider E, Paschke M, Ungewiss J, Haase C, Robillard L, Simmons AD, Harding TC, Nguyen M. Zboralski D, et al. Eur J Nucl Med Mol Imaging. 2023 Jul;50(9):2621-2635. doi: 10.1007/s00259-023-06211-6. Epub 2023 Apr 22. Eur J Nucl Med Mol Imaging. 2023. PMID: 37086273 Free PMC article.
Tumor uptake of (177)Lu- FAP-2287 was assessed by SPECT/CT scanning, while therapeutic efficacy was measured by tumor volume and survival. ...In flow cytometry analysis of tumors, (177)Lu-FAP-2287 increased CD8(+) T cell infiltration which was maintained in the comb …
Tumor uptake of (177)Lu- FAP-2287 was assessed by SPECT/CT scanning, while therapeutic efficacy was measured by tumor volume and surv …
27,657 results
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