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1989 1
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2018 1
2021 0
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Page 1
Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).
Come JH, Collier PN, Henderson JA, Pierce AC, Davies RJ, Le Tiran A, O'Dowd H, Bandarage UK, Cao J, Deininger D, Grey R, Krueger EB, Lowe DB, Liang J, Liao Y, Messersmith D, Nanthakumar S, Sizensky E, Wang J, Xu J, Chin EY, Damagnez V, Doran JD, Dworakowski W, Griffith JP, Jacobs MD, Khare-Pandit S, Mahajan S, Moody CS, Aronov AM. Come JH, et al. Among authors: damagnez v. J Med Chem. 2018 Jun 28;61(12):5245-5256. doi: 10.1021/acs.jmedchem.8b00085. Epub 2018 Jun 14. J Med Chem. 2018. PMID: 29847724
Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γ.
Collier PN, Messersmith D, Le Tiran A, Bandarage UK, Boucher C, Come J, Cottrell KM, Damagnez V, Doran JD, Griffith JP, Khare-Pandit S, Krueger EB, Ledeboer MW, Ledford B, Liao Y, Mahajan S, Moody CS, Roday S, Wang T, Xu J, Aronov AM. Collier PN, et al. Among authors: damagnez v. J Med Chem. 2015 Jul 23;58(14):5684-8. doi: 10.1021/acs.jmedchem.5b00498. Epub 2015 Jul 6. J Med Chem. 2015. PMID: 26121481
Pharmacological activation and inhibition of Slack (Slo2.2) channels.
Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. Yang B, et al. Among authors: damagnez v. Neuropharmacology. 2006 Sep;51(4):896-906. doi: 10.1016/j.neuropharm.2006.06.003. Epub 2006 Jul 28. Neuropharmacology. 2006. PMID: 16876206
Fission yeast Csk1 is a CAK-activating kinase (CAKAK).
Hermand D, Pihlak A, Westerling T, Damagnez V, Vandenhaute J, Cottarel G, Mäkelä TP. Hermand D, et al. Among authors: damagnez v. EMBO J. 1998 Dec 15;17(24):7230-8. doi: 10.1093/emboj/17.24.7230. EMBO J. 1998. PMID: 9857180 Free PMC article.
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