Darbyshire JF[au] - Search Results

Year	Number of Results
1966	1
1967	1
1992	1
1993	5
1994	6
1995	1
1996	1
1997	2
1998	1
2004	1
2005	1
2006	1
2009	1
2022	0

1

Inhibition of P450 cytochromes by reactive intermediates.

Osawa Y, Davila JC, Nakatsuka M, Meyer CA, Darbyshire JF. Osawa Y, et al. Among authors: darbyshire jf. Drug Metab Rev. 1995;27(1-2):61-72. doi: 10.3109/03602539509029815. Drug Metab Rev. 1995. PMID: 7641585 Review. No abstract available.

2

A review of the effects of manipulation of the cysteine residues of rat aryl sulfotransferase IV.

Marshall AD, Darbyshire JF, McPhie P, Jakoby WB. Marshall AD, et al. Among authors: darbyshire jf. Chem Biol Interact. 1998 Feb 20;109(1-3):107-16. doi: 10.1016/s0009-2797(97)00124-5. Chem Biol Interact. 1998. PMID: 9566737 Review.

3

Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.

Wagner R, Larson DP, Beno DW, Bosse TD, Darbyshire JF, Gao Y, Gates BD, He W, Henry RF, Hernandez LE, Hutchinson DK, Jiang WW, Kati WM, Klein LL, Koev G, Kohlbrenner W, Krueger AC, Liu J, Liu Y, Long MA, Maring CJ, Masse SV, Middleton T, Montgomery DA, Pratt JK, Stuart P, Molla A, Kempf DJ. Wagner R, et al. Among authors: darbyshire jf. J Med Chem. 2009 Mar 26;52(6):1659-69. doi: 10.1021/jm8010965. J Med Chem. 2009. PMID: 19226162

4

Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.

Patel MV, Kolasa T, Mortell K, Matulenko MA, Hakeem AA, Rohde JJ, Nelson SL, Cowart MD, Nakane M, Miller LN, Uchic ME, Terranova MA, El-Kouhen OF, Donnelly-Roberts DL, Namovic MT, Hollingsworth PR, Chang R, Martino BR, Wetter JM, Marsh KC, Martin R, Darbyshire JF, Gintant G, Hsieh GC, Moreland RB, Sullivan JP, Brioni JD, Stewart AO. Patel MV, et al. Among authors: darbyshire jf. J Med Chem. 2006 Dec 14;49(25):7450-65. doi: 10.1021/jm060662k. J Med Chem. 2006. PMID: 17149874

5

Structure-activity studies for a novel series of tricyclic dihydropyridopyrazolones and dihydropyridoisoxazolones as K(ATP) channel openers.

Drizin I, Altenbach RJ, Buckner SA, Whiteaker KL, Scott VE, Darbyshire JF, Jayanti V, Henry RF, Coghlan MJ, Gopalakrishnan M, Carroll WA. Drizin I, et al. Among authors: darbyshire jf. Bioorg Med Chem. 2004 Apr 15;12(8):1895-904. doi: 10.1016/j.bmc.2004.01.038. Bioorg Med Chem. 2004. PMID: 15051058

6

12 alpha-hydroxytestosterone. A hitherto unidentified testosterone metabolite produced by cytochrome P-450 2A2.

Smith SJ, Korzekwa KR, Aoyama T, Gonzalez FJ, Darbyshire JF, Sugiyama K, Gillette JR. Smith SJ, et al. Among authors: darbyshire jf. Drug Metab Dispos. 1992 Jul-Aug;20(4):566-71. Drug Metab Dispos. 1992. PMID: 1356736

7

Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent.

Wink DA, Osawa Y, Darbyshire JF, Jones CR, Eshenaur SC, Nims RW. Wink DA, et al. Among authors: darbyshire jf. Arch Biochem Biophys. 1993 Jan;300(1):115-23. doi: 10.1006/abbi.1993.1016. Arch Biochem Biophys. 1993. PMID: 8424643

8

Substrate probe for the mechanism of aromatic hydroxylation catalyzed by cytochrome P450.

Darbyshire JF, Iyer KR, Grogan J, Korzekwa KR, Trager WF. Darbyshire JF, et al. Drug Metab Dispos. 1996 Sep;24(9):1038-45. Drug Metab Dispos. 1996. PMID: 8886617

9

Control of activity through oxidative modification at the conserved residue Cys66 of aryl sulfotransferase IV.

Marshall AD, Darbyshire JF, Hunter AP, McPhie P, Jakoby WB. Marshall AD, et al. Among authors: darbyshire jf. J Biol Chem. 1997 Apr 4;272(14):9153-60. doi: 10.1074/jbc.272.14.9153. J Biol Chem. 1997. PMID: 9139043 Free article.

10

Differential susceptibilities of the prosthetic heme of hemoglobin-based red cell substitutes. Implications in the design of safer agents.

Osawa Y, Darbyshire JF, Meyer CA, Alayash AI. Osawa Y, et al. Among authors: darbyshire jf. Biochem Pharmacol. 1993 Dec 14;46(12):2299-305. doi: 10.1016/0006-2952(93)90621-3. Biochem Pharmacol. 1993. PMID: 8274164

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