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Page 1
KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas.
Heward J, Konali L, D'Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T, Al Seraihi AF, Wang J, Korfi K, Araf S, Iqbal S, Bewicke-Copley F, Kumar E, Barisic D, Calaminici M, Clear A, Gribben J, Johnson P, Neve R, Cutillas P, Okosun J, Oppermann U, Melnick A, Packham G, Fitzgibbon J. Heward J, et al. Blood. 2021 Aug 5;138(5):370-381. doi: 10.1182/blood.2020008743. Blood. 2021. PMID: 33786580 Free PMC article.
Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells.
Linley AJ, Karydis LI, Mondru AK, D'Avola A, Al Shmrany H, Cicconi S, Griffin R, Forconi F, Pettitt AR, Kalakonda N, Rawstron AC, Hillmen P, Steele AJ, MacEwan DJ, Packham G, Prior IA, Slupsky JR. Linley AJ, et al. Clin Cancer Res. 2021 Oct 15;27(20):5647-5659. doi: 10.1158/1078-0432.CCR-21-0161. Epub 2021 Aug 11. Clin Cancer Res. 2021. PMID: 34380642 Free PMC article.
High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in patients with CLL.
Chiodin G, Drennan S, Martino EA, Ondrisova L, Henderson I, Del Rio L, Tracy I, D'Avola A, Parker H, Bonfiglio S, Scarfò L, Sutton LA, Strefford JC, Forster J, Brake O, Potter KN, Sale B, Lanham S, Mraz M, Ghia P, Stevenson FK, Forconi F. Chiodin G, et al. Blood Adv. 2022 Sep 27;6(18):5494-5504. doi: 10.1182/bloodadvances.2021006659. Blood Adv. 2022. PMID: 35640238 Free PMC article.
12 results