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35 results

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Page 1
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators.
Dias SSG, Soares VC, Ferreira AC, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Teixeira L, Nunes da Silva MA, Barreto E, Mattos M, de Freitas CS, Azevedo-Quintanilha IG, Manso PPA, Miranda MD, Siqueira MM, Hottz ED, Pão CRR, Bou-Habib DC, Barreto-Vieira DF, Bozza FA, Souza TML, Bozza PT. Dias SSG, et al. Among authors: de freitas cs. PLoS Pathog. 2020 Dec 16;16(12):e1009127. doi: 10.1371/journal.ppat.1009127. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33326472 Free PMC article.
Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages.
Ferreira AC, Sacramento CQ, Pereira-Dutra FS, Fintelman-Rodrigues N, Silva PP, Mattos M, de Freitas CS, Marttorelli A, de Melo GR, Campos MM, Azevedo-Quintanilha IG, Carlos AS, Emídio JV, Garcia CC, Bozza PT, Bozza FA, Souza TML. Ferreira AC, et al. Among authors: de freitas cs. Front Cell Infect Microbiol. 2023 Feb 16;13:1067285. doi: 10.3389/fcimb.2023.1067285. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36875528 Free PMC article.
Unveiling the Antiviral Capabilities of Targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2.
Purificação AD, Silva-Mendonça S, Cruz LV, Sacramento CQ, Temerozo JR, Fintelman-Rodrigues N, de Freitas CS, Godoi BF, Vaidergorn MM, Leite JA, Salazar Alvarez LC, Freitas MV, Silvac MFB, Martin BA, Lopez RFV, Neves BJ, Costa FTM, Souza TML, da Silva Emery F, Andrade CH, Nonato MC. Purificação AD, et al. Among authors: de freitas cs. ACS Omega. 2024 Feb 28;9(10):11418-11430. doi: 10.1021/acsomega.3c07845. eCollection 2024 Mar 12. ACS Omega. 2024. PMID: 38496952 Free PMC article.
Agathisflavone, a natural biflavonoid that inhibits SARS-CoV-2 replication by targeting its proteases.
Chaves OA, Lima CR, Fintelman-Rodrigues N, Sacramento CQ, de Freitas CS, Vazquez L, Temerozo JR, Rocha MEN, Dias SSG, Carels N, Bozza PT, Castro-Faria-Neto HC, Souza TML. Chaves OA, et al. Among authors: de freitas cs. Int J Biol Macromol. 2022 Dec 1;222(Pt A):1015-1026. doi: 10.1016/j.ijbiomac.2022.09.204. Epub 2022 Sep 29. Int J Biol Macromol. 2022. PMID: 36183752 Free PMC article.
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes.
Ferreira AC, Soares VC, de Azevedo-Quintanilha IG, Dias SDSG, Fintelman-Rodrigues N, Sacramento CQ, Mattos M, de Freitas CS, Temerozo JR, Teixeira L, Damaceno Hottz E, Barreto EA, Pão CRR, Palhinha L, Miranda M, Bou-Habib DC, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Among authors: de freitas cs. Cell Death Discov. 2021 Mar 1;7(1):43. doi: 10.1038/s41420-021-00428-w. Cell Death Discov. 2021. PMID: 33649297 Free PMC article.
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts.
Teixeira L, Temerozo JR, Pereira-Dutra FS, Ferreira AC, Mattos M, Gonçalves BS, Sacramento CQ, Palhinha L, Cunha-Fernandes T, Dias SSG, Soares VC, Barreto EA, Cesar-Silva D, Fintelman-Rodrigues N, Pão CRR, de Freitas CS, Reis PA, Hottz ED, Bozza FA, Bou-Habib DC, Saraiva EM, de Almeida CJG, Viola JPB, Souza TML, Bozza PT. Teixeira L, et al. Among authors: de freitas cs. Front Immunol. 2022 Feb 18;13:820131. doi: 10.3389/fimmu.2022.820131. eCollection 2022. Front Immunol. 2022. PMID: 35251001 Free PMC article.
Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes.
Ferreira AC, Soares VC, de Azevedo-Quintanilha IG, Dias SDSG, Fintelman-Rodrigues N, Sacramento CQ, Mattos M, de Freitas CS, Temerozo JR, Teixeira L, Hottz ED, Barreto EA, Pão CRR, Palhinha L, Miranda M, Bou-Habib DC, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Among authors: de freitas cs. Cell Death Discov. 2021 May 19;7(1):116. doi: 10.1038/s41420-021-00477-1. Cell Death Discov. 2021. PMID: 34011951 Free PMC article. No abstract available.
Agathisflavone, a Biflavonoid from Anacardium occidentale L., Inhibits Influenza Virus Neuraminidase.
de Freitas CS, Rocha MEN, Sacramento CQ, Marttorelli A, Ferreira AC, Rocha N, de Oliveira AC, de Oliveira Gomes AM, Dos Santos PS, da Silva EO, da Costa JP, de Lima Moreira D, Bozza PT, Silva JL, Barroso SPC, Souza TML. de Freitas CS, et al. Curr Top Med Chem. 2020;20(2):111-120. doi: 10.2174/1568026620666191219150738. Curr Top Med Chem. 2020. PMID: 31854280
35 results