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Page 1
Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents.
Battin C, De Sousa Linhares A, Leitner J, Grossmann A, Lupinek D, Izadi S, Castilho A, Waidhofer-Söllner P, Grabmeier-Pfistershammer K, Stritzker J, Steinberger P. Battin C, et al. Among authors: de sousa linhares a. Cancer Immunol Immunother. 2023 Sep;72(9):3029-3043. doi: 10.1007/s00262-023-03474-8. Epub 2023 Jun 13. Cancer Immunol Immunother. 2023. PMID: 37310433 Free PMC article.
Not All Immune Checkpoints Are Created Equal.
De Sousa Linhares A, Leitner J, Grabmeier-Pfistershammer K, Steinberger P. De Sousa Linhares A, et al. Front Immunol. 2018 Aug 31;9:1909. doi: 10.3389/fimmu.2018.01909. eCollection 2018. Front Immunol. 2018. PMID: 30233564 Free PMC article. Review.
Neuropilin-1 Acts as a Receptor for Complement Split Products.
Battin C, De Sousa Linhares A, Paster W, Isenman DE, Wahrmann M, Leitner J, Zlabinger GJ, Steinberger P, Hofer J. Battin C, et al. Among authors: de sousa linhares a. Front Immunol. 2019 Sep 13;10:2209. doi: 10.3389/fimmu.2019.02209. eCollection 2019. Front Immunol. 2019. PMID: 31572401 Free PMC article.
TIM-3 and CEACAM1 do not interact in cis and in trans.
De Sousa Linhares A, Kellner F, Jutz S, Zlabinger GJ, Gabius HJ, Huppa JB, Leitner J, Steinberger P. De Sousa Linhares A, et al. Eur J Immunol. 2020 Aug;50(8):1126-1141. doi: 10.1002/eji.201948400. Epub 2020 Apr 28. Eur J Immunol. 2020. PMID: 32222966 Free PMC article.
A New Strategy Toward B Cell-Based Cancer Vaccines by Active Immunization With Mimotopes of Immune Checkpoint Inhibitors.
Tobias J, Battin C, De Sousa Linhares A, Lebens M, Baier K, Ambroz K, Drinić M, Högler S, Inic-Kanada A, Garner-Spitzer E, Preusser M, Kenner L, Kundi M, Zielinski CC, Steinberger P, Wiedermann U. Tobias J, et al. Among authors: de sousa linhares a. Front Immunol. 2020 May 27;11:895. doi: 10.3389/fimmu.2020.00895. eCollection 2020. Front Immunol. 2020. PMID: 32528470 Free PMC article.
A conformation-specific ON-switch for controlling CAR T cells with an orally available drug.
Zajc CU, Dobersberger M, Schaffner I, Mlynek G, Pühringer D, Salzer B, Djinović-Carugo K, Steinberger P, De Sousa Linhares A, Yang NJ, Obinger C, Holter W, Traxlmayr MW, Lehner M. Zajc CU, et al. Among authors: de sousa linhares a. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):14926-14935. doi: 10.1073/pnas.1911154117. Epub 2020 Jun 17. Proc Natl Acad Sci U S A. 2020. PMID: 32554495 Free PMC article.