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MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells.
Röring RJ, Debisarun PA, Botey-Bataller J, Suen TK, Bulut Ö, Kilic G, Koeken VA, Sarlea A, Bahrar H, Dijkstra H, Lemmers H, Gössling KL, Rüchel N, Ostermann PN, Müller L, Schaal H, Adams O, Borkhardt A, Ariyurek Y, de Meijer EJ, Kloet SL, Ten Oever J, Placek K, Li Y, Netea MG. Röring RJ, et al. Among authors: debisarun pa. J Clin Invest. 2024 Jan 30;134(7):e170848. doi: 10.1172/JCI170848. J Clin Invest. 2024. PMID: 38290093 Free PMC article. Clinical Trial.
Fatty acid desaturation and lipoxygenase pathways support trained immunity.
Ferreira AV, Alarcon-Barrera JC, Domínguez-Andrés J, Bulut Ö, Kilic G, Debisarun PA, Röring RJ, Özhan HN, Terschlüsen E, Ziogas A, Kostidis S, Mohammed Y, Matzaraki V, Renieris G, Giamarellos-Bourboulis EJ, Netea MG, Giera M. Ferreira AV, et al. Among authors: debisarun pa. Nat Commun. 2023 Nov 15;14(1):7385. doi: 10.1038/s41467-023-43315-x. Nat Commun. 2023. PMID: 37968313 Free PMC article.
Seasonal variation in BCG-induced trained immunity.
Kilic G, Debisarun PA, Alaswad A, Baltissen MP, Lamers LA, de Bree LCJ, Benn CS, Aaby P, Dijkstra H, Lemmers H, Martens JHA, Domínguez-Andrés J, van Crevel R, Li Y, Xu CJ, Netea MG. Kilic G, et al. Among authors: debisarun pa. Vaccine. 2024 Oct 24;42(24):126109. doi: 10.1016/j.vaccine.2024.07.010. Epub 2024 Jul 8. Vaccine. 2024. PMID: 38981740 Free article.
Alendronate modulates cytokine responses in healthy young individuals after BCG vaccination.
Bulut O, Kilic G, Debisarun PA, Röring RJ, Sun S, Kolkman M, van Rijssen E, Ten Oever J, Koenen H, Barreiro L, Domínguez-Andrés J, Netea MG. Bulut O, et al. Among authors: debisarun pa. Immunol Lett. 2024 Jun;267:106851. doi: 10.1016/j.imlet.2024.106851. Epub 2024 Mar 11. Immunol Lett. 2024. PMID: 38479480 Free PMC article. Clinical Trial.
In vitro induction of trained immunity in adherent human monocytes.
Domínguez-Andrés J, Arts RJW, Bekkering S, Bahrar H, Blok BA, de Bree LCJ, Bruno M, Bulut Ö, Debisarun PA, Dijkstra H, Cristina Dos Santos J, Ferreira AV, Flores-Gomez D, Groh LA, Grondman I, Helder L, Jacobs C, Jacobs L, Jansen T, Kilic G, Klück V, Koeken VACM, Lemmers H, Moorlag SJCFM, Mourits VP, van Puffelen JH, Rabold K, Röring RJ, Rosati D, Tercan H, van Tuijl J, Quintin J, van Crevel R, Riksen NP, Joosten LAB, Netea MG. Domínguez-Andrés J, et al. Among authors: debisarun pa. STAR Protoc. 2021 Feb 24;2(1):100365. doi: 10.1016/j.xpro.2021.100365. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33718890 Free PMC article.
The impact of BCG dose and revaccination on trained immunity.
Debisarun PA, Kilic G, de Bree LCJ, Pennings LJ, van Ingen J, Benn CS, Aaby P, Dijkstra H, Lemmers H, Domínguez-Andrés J, van Crevel R, Netea MG. Debisarun PA, et al. Clin Immunol. 2023 Jan;246:109208. doi: 10.1016/j.clim.2022.109208. Epub 2022 Dec 21. Clin Immunol. 2023. PMID: 36565972 Free article. Clinical Trial.
Induction of trained immunity by influenza vaccination - impact on COVID-19.
Debisarun PA, Gössling KL, Bulut O, Kilic G, Zoodsma M, Liu Z, Oldenburg M, Rüchel N, Zhang B, Xu CJ, Struycken P, Koeken VACM, Domínguez-Andrés J, Moorlag SJCFM, Taks E, Ostermann PN, Müller L, Schaal H, Adams O, Borkhardt A, Ten Oever J, van Crevel R, Li Y, Netea MG. Debisarun PA, et al. PLoS Pathog. 2021 Oct 25;17(10):e1009928. doi: 10.1371/journal.ppat.1009928. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34695164 Free PMC article.
Determinants of Systemic SARS-CoV-2-Specific Antibody Responses to Infection and to Vaccination: A Secondary Analysis of Randomised Controlled Trial Data.
Claus J, Ten Doesschate T, Taks E, Debisarun PA, Smits G, van Binnendijk R, van der Klis F, Verhagen LM, de Jonge MI, Bonten MJM, Netea MG, van de Wijgert JHHM. Claus J, et al. Among authors: debisarun pa. Vaccines (Basel). 2024 Jun 20;12(6):691. doi: 10.3390/vaccines12060691. Vaccines (Basel). 2024. PMID: 38932420 Free PMC article.
14 results