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Page 1
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence.
Desdín-Micó G, Soto-Heredero G, Aranda JF, Oller J, Carrasco E, Gabandé-Rodríguez E, Blanco EM, Alfranca A, Cussó L, Desco M, Ibañez B, Gortazar AR, Fernández-Marcos P, Navarro MN, Hernaez B, Alcamí A, Baixauli F, Mittelbrunn M. Desdín-Micó G, et al. Science. 2020 Jun 19;368(6497):1371-1376. doi: 10.1126/science.aax0860. Epub 2020 May 21. Science. 2020. PMID: 32439659
The role of T cells in age-related diseases.
Carrasco E, Gómez de Las Heras MM, Gabandé-Rodríguez E, Desdín-Micó G, Aranda JF, Mittelbrunn M. Carrasco E, et al. Among authors: desdin mico g. Nat Rev Immunol. 2022 Feb;22(2):97-111. doi: 10.1038/s41577-021-00557-4. Epub 2021 Jun 7. Nat Rev Immunol. 2022. PMID: 34099898 Review.
Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.
Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Redondo JM, Mittelbrunn M. Oller J, et al. Among authors: desdin mico g. Circulation. 2021 May 25;143(21):2091-2109. doi: 10.1161/CIRCULATIONAHA.120.051171. Epub 2021 Mar 12. Circulation. 2021. PMID: 33709773 Free PMC article.
Mitochondrial activity in T cells.
Desdín-Micó G, Soto-Heredero G, Mittelbrunn M. Desdín-Micó G, et al. Mitochondrion. 2018 Jul;41:51-57. doi: 10.1016/j.mito.2017.10.006. Epub 2017 Oct 12. Mitochondrion. 2018. PMID: 29032101 Free article. Review.
Mitochondrial dysfunction defines T cell exhaustion.
Soto-Heredero G, Desdín-Micó G, Mittelbrunn M. Soto-Heredero G, et al. Among authors: desdin mico g. Cell Metab. 2021 Mar 2;33(3):470-472. doi: 10.1016/j.cmet.2021.02.010. Cell Metab. 2021. PMID: 33657392 Free article.
Role of exosomes in the protection of cellular homeostasis.
Desdín-Micó G, Mittelbrunn M. Desdín-Micó G, et al. Cell Adh Migr. 2017 Mar 4;11(2):127-134. doi: 10.1080/19336918.2016.1251000. Epub 2016 Nov 22. Cell Adh Migr. 2017. PMID: 27875097 Free PMC article. Review.
The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function.
Caravia XM, Fanjul V, Oliver E, Roiz-Valle D, Morán-Álvarez A, Desdín-Micó G, Mittelbrunn M, Cabo R, Vega JA, Rodríguez F, Fueyo A, Gómez M, Lobo-González M, Bueno H, Velasco G, Freije JMP, Andrés V, Ibáñez B, Ugalde AP, López-Otín C. Caravia XM, et al. Among authors: desdin mico g. PLoS Biol. 2018 Oct 22;16(10):e2006247. doi: 10.1371/journal.pbio.2006247. eCollection 2018 Oct. PLoS Biol. 2018. PMID: 30346946 Free PMC article.