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2009 1
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Page 1
Structurally Diverse Diterpenoids from Sandwithia guyanensis.
Remy S, Olivon F, Desrat S, Blanchard F, Eparvier V, Leyssen P, Neyts J, Roussi F, Touboul D, Litaudon M. Remy S, et al. Among authors: desrat s. J Nat Prod. 2018 Apr 27;81(4):901-912. doi: 10.1021/acs.jnatprod.7b01025. Epub 2018 Mar 1. J Nat Prod. 2018. PMID: 29493237
Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1.
Daressy F, Malard F, Seguy L, Guérineau V, Apel C, Dumontet V, Robert A, Groo AC, Litaudon M, Bignon J, Desrat S, Malzert-Fréon A, Wiels J, Lescop E, Roussi F. Daressy F, et al. Among authors: desrat s. ChemMedChem. 2021 Jun 7;16(11):1788-1797. doi: 10.1002/cmdc.202100011. Epub 2021 Mar 23. ChemMedChem. 2021. PMID: 33665938
Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2.
Gapil Tiamas S, Daressy F, Abou Samra A, Bignon J, Steinmetz V, Litaudon M, Fourneau C, Hoong Leong K, Ariffin A, Awang K, Desrat S, Roussi F. Gapil Tiamas S, et al. Among authors: desrat s. Bioorg Med Chem Lett. 2020 Apr 1;30(7):127003. doi: 10.1016/j.bmcl.2020.127003. Epub 2020 Feb 3. Bioorg Med Chem Lett. 2020. PMID: 32035700
NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes.
Daressy F, Séguy L, Favre L, Corvaisier S, Apel C, Groo AC, Litaudon M, Dumontet V, Malzert-Fréon A, Desrat S, Roussi F, Robert A, Wiels J. Daressy F, et al. Among authors: desrat s. Biomed Pharmacother. 2022 Oct;154:113546. doi: 10.1016/j.biopha.2022.113546. Epub 2022 Aug 18. Biomed Pharmacother. 2022. PMID: 35988426 Free article.
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
Desrat S, Pujals A, Colas C, Dardenne J, Gény C, Favre L, Dumontet V, Iorga BI, Litaudon M, Raphaël M, Wiels J, Roussi F. Desrat S, et al. Bioorg Med Chem Lett. 2014 Nov 1;24(21):5086-8. doi: 10.1016/j.bmcl.2014.09.004. Epub 2014 Sep 6. Bioorg Med Chem Lett. 2014. PMID: 25266781 Free article.
Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitor.
Péresse T, Kovacs D, Subra M, Bigay J, Tsai MC, Polidori J, Gautier R, Desrat S, Fleuriot L, Debayle D, Litaudon M, Pham VC, Bignon J, Antonny B, Roussi F, Mesmin B. Péresse T, et al. Among authors: desrat s. J Biol Chem. 2020 Mar 27;295(13):4277-4288. doi: 10.1074/jbc.RA119.012012. Epub 2020 Feb 19. J Biol Chem. 2020. PMID: 32075908 Free PMC article.
15 results