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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 2
2006 2
2007 2
2008 5
2009 6
2010 12
2011 7
2012 3
2013 5
2014 7
2015 1
2016 2
2017 3
2018 4
2019 6
2020 5
2021 1
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63 results
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Page 1
A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.
Liang Q, Dexheimer TS, Zhang P, Rosenthal AS, Villamil MA, You C, Zhang Q, Chen J, Ott CA, Sun H, Luci DK, Yuan B, Simeonov A, Jadhav A, Xiao H, Wang Y, Maloney DJ, Zhuang Z. Liang Q, et al. Among authors: dexheimer ts. Nat Chem Biol. 2014 Apr;10(4):298-304. doi: 10.1038/nchembio.1455. Epub 2014 Feb 16. Nat Chem Biol. 2014. PMID: 24531842 Free PMC article.
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.
Stafford WC, Peng X, Olofsson MH, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ. Stafford WC, et al. Among authors: dexheimer ts. Sci Transl Med. 2018 Feb 14;10(428):eaaf7444. doi: 10.1126/scitranslmed.aaf7444. Sci Transl Med. 2018. PMID: 29444979 Free PMC article.
A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.
Nguyen GH, Dexheimer TS, Rosenthal AS, Chu WK, Singh DK, Mosedale G, Bachrati CZ, Schultz L, Sakurai M, Savitsky P, Abu M, McHugh PJ, Bohr VA, Harris CC, Jadhav A, Gileadi O, Maloney DJ, Simeonov A, Hickson ID. Nguyen GH, et al. Among authors: dexheimer ts. Chem Biol. 2013 Jan 24;20(1):55-62. doi: 10.1016/j.chembiol.2012.10.016. Chem Biol. 2013. PMID: 23352139 Free PMC article.
Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death.
Liu M, Sui D, Dexheimer T, Hovde S, Deng X, Wang KW, Lin HL, Chien HT, Kweon HK, Kuo NS, Ayoub CA, Jimenez-Harrison D, Andrews PC, Kwok R, Bochar DA, Kuret J, Fortin J, Tsay YG, Kuo MH. Liu M, et al. Among authors: dexheimer t. Mol Neurobiol. 2020 Nov;57(11):4704-4719. doi: 10.1007/s12035-020-02034-w. Epub 2020 Aug 11. Mol Neurobiol. 2020. PMID: 32780352
Spermine in semen of male sea lamprey acts as a sex pheromone.
Scott AM, Zhang Z, Jia L, Li K, Zhang Q, Dexheimer T, Ellsworth E, Ren J, Chung-Davidson YW, Zu Y, Neubig RR, Li W. Scott AM, et al. Among authors: dexheimer t. PLoS Biol. 2019 Jul 9;17(7):e3000332. doi: 10.1371/journal.pbio.3000332. eCollection 2019 Jul. PLoS Biol. 2019. PMID: 31287811 Free PMC article.
63 results
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