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Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
Loyal L, Braun J, Henze L, Kruse B, Dingeldey M, Reimer U, Kern F, Schwarz T, Mangold M, Unger C, Dörfler F, Kadler S, Rosowski J, Gürcan K, Uyar-Aydin Z, Frentsch M, Kurth F, Schnatbaum K, Eckey M, Hippenstiel S, Hocke A, Müller MA, Sawitzki B, Miltenyi S, Paul F, Mall MA, Wenschuh H, Voigt S, Drosten C, Lauster R, Lachman N, Sander LE, Corman VM, Röhmel J, Meyer-Arndt L, Thiel A, Giesecke-Thiel C. Loyal L, et al. Among authors: dingeldey m. Science. 2021 Oct 8;374(6564):eabh1823. doi: 10.1126/science.abh1823. Epub 2021 Oct 8. Science. 2021. PMID: 34465633 Free PMC article.
Primary ChAdOx1 vaccination does not reactivate pre-existing, cross-reactive immunity.
Henze L, Braun J, Meyer-Arndt L, Jürchott K, Schlotz M, Michel J, Grossegesse M, Mangold M, Dingeldey M, Kruse B, Holenya P, Mages N, Reimer U, Eckey M, Schnatbaum K, Wenschuh H, Timmermann B, Klein F, Nitsche A, Giesecke-Thiel C, Loyal L, Thiel A. Henze L, et al. Among authors: dingeldey m. Front Immunol. 2023 Jan 31;14:1056525. doi: 10.3389/fimmu.2023.1056525. eCollection 2023. Front Immunol. 2023. PMID: 36798117 Free PMC article.
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19.
Braun J, Loyal L, Frentsch M, Wendisch D, Georg P, Kurth F, Hippenstiel S, Dingeldey M, Kruse B, Fauchere F, Baysal E, Mangold M, Henze L, Lauster R, Mall MA, Beyer K, Röhmel J, Voigt S, Schmitz J, Miltenyi S, Demuth I, Müller MA, Hocke A, Witzenrath M, Suttorp N, Kern F, Reimer U, Wenschuh H, Drosten C, Corman VM, Giesecke-Thiel C, Sander LE, Thiel A. Braun J, et al. Among authors: dingeldey m. Nature. 2020 Nov;587(7833):270-274. doi: 10.1038/s41586-020-2598-9. Epub 2020 Jul 29. Nature. 2020. PMID: 32726801
Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4+ T Cells following BNT162b2 Vaccination in the Elderly.
Meyer-Arndt L, Schwarz T, Loyal L, Henze L, Kruse B, Dingeldey M, Gürcan K, Uyar-Aydin Z, Müller MA, Drosten C, Paul F, Sander LE, Demuth I, Lauster R, Giesecke-Thiel C, Braun J, Corman VM, Thiel A. Meyer-Arndt L, et al. Among authors: dingeldey m. J Immunol. 2022 Mar 1;208(5):1001-1005. doi: 10.4049/jimmunol.2100990. Epub 2022 Feb 4. J Immunol. 2022. PMID: 35121642
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt L, Braun J, Fauchere F, Vanshylla K, Loyal L, Henze L, Kruse B, Dingeldey M, Jürchott K, Mangold M, Maraj A, Braginets A, Böttcher C, Nitsche A, de la Rosa K, Ratswohl C, Sawitzki B, Holenya P, Reimer U, Sander LE, Klein F, Paul F, Bellmann-Strobl J, Thiel A, Giesecke-Thiel C. Meyer-Arndt L, et al. Among authors: dingeldey m. J Neurol Neurosurg Psychiatry. 2022 Sep;93(9):960-971. doi: 10.1136/jnnp-2022-329395. Epub 2022 Jul 14. J Neurol Neurosurg Psychiatry. 2022. PMID: 35835468 Free PMC article.