Genome-wide significant risk factors on chromosome 19 and the APOE locus.
Moreno-Grau S, Hernández I, Heilmann-Heimbach S, Ruiz S, Rosende-Roca M, Mauleón A, Vargas L, Rodríguez-Gómez O, Alegret M, Espinosa A, Ortega G, Aguilera N, Abdelnour C, Neuroimaging Initiative AD, Gil S, Maier W, Sotolongo-Grau O, Tárraga L, Ramirez A, López-Arrrieta J, Antúnez C, Serrano-Ríos M, Boada M, Ruiz A.
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Oncotarget. 2018 May 15;9(37):24590-24600. doi: 10.18632/oncotarget.25083. eCollection 2018 May 15.
Oncotarget. 2018.
PMID: 29872490
Free PMC article.
The apolipoprotein E (APOE) gene on chromosome 19q13.32, was the first, and remains the strongest, genetic risk factor for Alzheimer's disease (AD). Additional signals associated with AD have been located in chromosome 19, including ABCA7 (19p13.3) and CD33 (19q13.41). ...
The apolipoprotein E (APOE) gene on chromosome 19q13.32, was the first, and remains the strongest, genetic risk factor for Alzheimer's di …