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Repression of T-cell function by thionamides is mediated by inhibition of the activator protein-1/nuclear factor of activated T-cells pathway and is associated with a common structure.
Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Heimrich B, Roesslein M, Schmidt R, Schwer CI, Hoetzel A, Loop T, Pahl HL, Geiger KK, Pannen BH. Humar M, et al. Among authors: dohrmann h. Mol Pharmacol. 2007 Dec;72(6):1647-56. doi: 10.1124/mol.107.038141. Epub 2007 Sep 18. Mol Pharmacol. 2007. PMID: 17878268