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Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-thienylmethyl)-4H-pyrrolo[3,2-d] pyrimidin-4-one.
Sircar JC, Kostlan CR, Gilbertsen RB, Bennett MK, Dong MK, Cetenko WJ. Sircar JC, et al. Among authors: dong mk. J Med Chem. 1992 May 1;35(9):1605-9. doi: 10.1021/jm00087a015. J Med Chem. 1992. PMID: 1578487
26 results