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Year Number of Results
2008 1
2009 1
2013 1
2014 2
2017 2
2018 2
2019 1
2021 1
2022 1
2023 1

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11 results

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Page 1
Structural basis for Cas9 off-target activity.
Pacesa M, Lin CH, Cléry A, Saha A, Arantes PR, Bargsten K, Irby MJ, Allain FH, Palermo G, Cameron P, Donohoue PD, Jinek M. Pacesa M, et al. Among authors: donohoue pd. Cell. 2022 Oct 27;185(22):4067-4081.e21. doi: 10.1016/j.cell.2022.09.026. Cell. 2022. PMID: 36306733 Free PMC article.
Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Cameron P, Fuller CK, Donohoue PD, Jones BN, Thompson MS, Carter MM, Gradia S, Vidal B, Garner E, Slorach EM, Lau E, Banh LM, Lied AM, Edwards LS, Settle AH, Capurso D, Llaca V, Deschamps S, Cigan M, Young JK, May AP. Cameron P, et al. Among authors: donohoue pd. Nat Methods. 2017 Jun;14(6):600-606. doi: 10.1038/nmeth.4284. Epub 2017 May 1. Nat Methods. 2017. PMID: 28459459
NmeCas9 is an intrinsically high-fidelity genome-editing platform.
Amrani N, Gao XD, Liu P, Edraki A, Mir A, Ibraheim R, Gupta A, Sasaki KE, Wu T, Donohoue PD, Settle AH, Lied AM, McGovern K, Fuller CK, Cameron P, Fazzio TG, Zhu LJ, Wolfe SA, Sontheimer EJ. Amrani N, et al. Among authors: donohoue pd. Genome Biol. 2018 Dec 5;19(1):214. doi: 10.1186/s13059-018-1591-1. Genome Biol. 2018. PMID: 30518407 Free PMC article.
Harnessing type I CRISPR-Cas systems for genome engineering in human cells.
Cameron P, Coons MM, Klompe SE, Lied AM, Smith SC, Vidal B, Donohoue PD, Rotstein T, Kohrs BW, Nyer DB, Kennedy R, Banh LM, Williams C, Toh MS, Irby MJ, Edwards LS, Lin CH, Owen ALG, Künne T, van der Oost J, Brouns SJJ, Slorach EM, Fuller CK, Gradia S, Kanner SB, May AP, Sternberg SH. Cameron P, et al. Among authors: donohoue pd. Nat Biotechnol. 2019 Dec;37(12):1471-1477. doi: 10.1038/s41587-019-0310-0. Epub 2019 Nov 18. Nat Biotechnol. 2019. PMID: 31740839
Allogeneic chimeric antigen receptor-T cells with CRISPR-disrupted programmed death-1 checkpoint exhibit enhanced functional fitness.
Lau E, Kwong G, Fowler TW, Sun BC, Donohoue PD, Davis RT, Bryan M, McCawley S, Clarke SC, Williams C, Banh L, Irby M, Edwards L, Storlie M, Kohrs B, Lilley GWJ, Smith SC, Gradia S, Fuller CK, Skoble J, Garner E, van Overbeek M, Kanner SB. Lau E, et al. Among authors: donohoue pd. Cytotherapy. 2023 Jul;25(7):750-762. doi: 10.1016/j.jcyt.2023.03.011. Epub 2023 Apr 21. Cytotherapy. 2023. PMID: 37086241 Free article.
Guide RNA functional modules direct Cas9 activity and orthogonality.
Briner AE, Donohoue PD, Gomaa AA, Selle K, Slorach EM, Nye CH, Haurwitz RE, Beisel CL, May AP, Barrangou R. Briner AE, et al. Among authors: donohoue pd. Mol Cell. 2014 Oct 23;56(2):333-339. doi: 10.1016/j.molcel.2014.09.019. Epub 2014 Oct 16. Mol Cell. 2014. PMID: 25373540 Free article.
Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform.
Enquist-Newman M, Faust AM, Bravo DD, Santos CN, Raisner RM, Hanel A, Sarvabhowman P, Le C, Regitsky DD, Cooper SR, Peereboom L, Clark A, Martinez Y, Goldsmith J, Cho MY, Donohoue PD, Luo L, Lamberson B, Tamrakar P, Kim EJ, Villari JL, Gill A, Tripathi SA, Karamchedu P, Paredes CJ, Rajgarhia V, Kotlar HK, Bailey RB, Miller DJ, Ohler NL, Swimmer C, Yoshikuni Y. Enquist-Newman M, et al. Among authors: donohoue pd. Nature. 2014 Jan 9;505(7482):239-43. doi: 10.1038/nature12771. Epub 2013 Dec 1. Nature. 2014. PMID: 24291791
11 results