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Antioxidants in the canine model of human aging.

Dowling AL, Head E. Dowling AL, et al. Biochim Biophys Acta. 2012 May;1822(5):685-9. doi: 10.1016/j.bbadis.2011.09.020. Epub 2011 Oct 8. Biochim Biophys Acta. 2012. PMID: 22005070 Free PMC article. Review.

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Thyroid hormone, brain development, and the environment.

Zoeller TR, Dowling AL, Herzig CT, Iannacone EA, Gauger KJ, Bansal R. Zoeller TR, et al. Among authors: dowling al. Environ Health Perspect. 2002 Jun;110 Suppl 3(Suppl 3):355-61. doi: 10.1289/ehp.02110s3355. Environ Health Perspect. 2002. PMID: 12060829 Free PMC article. Review.

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BACE2 expression increases in human neurodegenerative disease.

Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. Holler CJ, et al. Among authors: dowling al. Am J Pathol. 2012 Jan;180(1):337-50. doi: 10.1016/j.ajpath.2011.09.034. Epub 2011 Nov 7. Am J Pathol. 2012. PMID: 22074738 Free PMC article.

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Coenzyme Q10 and cognition in atorvastatin treated dogs.

Martin SB, Cenini G, Barone E, Dowling AL, Mancuso C, Butterfield DA, Murphy MP, Head E. Martin SB, et al. Among authors: dowling al. Neurosci Lett. 2011 Aug 26;501(2):92-5. doi: 10.1016/j.neulet.2011.06.054. Epub 2011 Jul 8. Neurosci Lett. 2011. PMID: 21763754 Free PMC article.

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Therapeutic interventions targeting Beta amyloid pathogenesis in an aging dog model.

Martin SB, Dowling AL, Head E. Martin SB, et al. Among authors: dowling al. Curr Neuropharmacol. 2011 Dec;9(4):651-61. doi: 10.2174/157015911798376217. Curr Neuropharmacol. 2011. PMID: 22654723 Free PMC article.

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Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's disease.

Martin SB, Dowling AL, Lianekhammy J, Lott IT, Doran E, Murphy MP, Beckett TL, Schmitt FA, Head E. Martin SB, et al. Among authors: dowling al. J Alzheimers Dis. 2014;42(3):767-75. doi: 10.3233/JAD-140795. J Alzheimers Dis. 2014. PMID: 24927707 Free PMC article.

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Hippocampal CA1 transcriptional profile of sleep deprivation: relation to aging and stress.

Porter NM, Bohannon JH, Curran-Rauhut M, Buechel HM, Dowling AL, Brewer LD, Popovic J, Thibault V, Kraner SD, Chen KC, Blalock EM. Porter NM, et al. Among authors: dowling al. PLoS One. 2012;7(7):e40128. doi: 10.1371/journal.pone.0040128. Epub 2012 Jul 5. PLoS One. 2012. PMID: 22792227 Free PMC article.

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RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease.

Weidner AM, Bradley MA, Beckett TL, Niedowicz DM, Dowling AL, Matveev SV, LeVine H 3rd, Lovell MA, Murphy MP. Weidner AM, et al. Among authors: dowling al. PLoS One. 2011;6(9):e24930. doi: 10.1371/journal.pone.0024930. Epub 2011 Sep 20. PLoS One. 2011. PMID: 21949792 Free PMC article.

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Estradiol reverses a calcium-related biomarker of brain aging in female rats.

Brewer LD, Dowling AL, Curran-Rauhut MA, Landfield PW, Porter NM, Blalock EM. Brewer LD, et al. Among authors: dowling al. J Neurosci. 2009 May 13;29(19):6058-67. doi: 10.1523/JNEUROSCI.5253-08.2009. J Neurosci. 2009. PMID: 19439583 Free PMC article.

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Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome.

Cenini G, Dowling AL, Beckett TL, Barone E, Mancuso C, Murphy MP, Levine H 3rd, Lott IT, Schmitt FA, Butterfield DA, Head E. Cenini G, et al. Among authors: dowling al. Biochim Biophys Acta. 2012 Feb;1822(2):130-8. doi: 10.1016/j.bbadis.2011.10.001. Epub 2011 Oct 8. Biochim Biophys Acta. 2012. PMID: 22009041 Free PMC article.

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