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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2004 1
2005 2
2007 3
2009 1
2010 1
2012 2
2014 2
2015 7
2016 5
2017 5
2018 12
2019 8
2020 12
2021 10
2022 6
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69 results
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Page 1
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
Heijerman HGM, McKone EF, Downey DG, Van Braeckel E, Rowe SM, Tullis E, Mall MA, Welter JJ, Ramsey BW, McKee CM, Marigowda G, Moskowitz SM, Waltz D, Sosnay PR, Simard C, Ahluwalia N, Xuan F, Zhang Y, Taylor-Cousar JL, McCoy KS; VX17-445-103 Trial Group. Heijerman HGM, et al. Among authors: downey dg. Lancet. 2019 Nov 23;394(10212):1940-1948. doi: 10.1016/S0140-6736(19)32597-8. Epub 2019 Oct 31. Lancet. 2019. PMID: 31679946 Free PMC article. Clinical Trial.
Rebuttal From Dr Downey.
Downey DG. Downey DG. Chest. 2022 Jan;161(1):24. doi: 10.1016/j.chest.2021.06.019. Chest. 2022. PMID: 35000703 No abstract available.
Theratyping in cystic fibrosis.
Crawford KJ, Downey DG. Crawford KJ, et al. Among authors: downey dg. Curr Opin Pulm Med. 2018 Nov;24(6):612-617. doi: 10.1097/MCP.0000000000000521. Curr Opin Pulm Med. 2018. PMID: 30124524 Review.
Tackling bias in clinical trials.
van Koningsbruggen-Rietschel S, Downey DG. van Koningsbruggen-Rietschel S, et al. Among authors: downey dg. J Cyst Fibros. 2019 Jul;18(4):445-446. doi: 10.1016/j.jcf.2019.06.001. J Cyst Fibros. 2019. PMID: 31230796 Free article. No abstract available.
Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.
Sutharsan S, McKone EF, Downey DG, Duckers J, MacGregor G, Tullis E, Van Braeckel E, Wainwright CE, Watson D, Ahluwalia N, Bruinsma BG, Harris C, Lam AP, Lou Y, Moskowitz SM, Tian S, Yuan J, Waltz D, Mall MA; VX18-445-109 study group. Sutharsan S, et al. Among authors: downey dg. Lancet Respir Med. 2022 Mar;10(3):267-277. doi: 10.1016/S2213-2600(21)00454-9. Epub 2021 Dec 20. Lancet Respir Med. 2022. PMID: 34942085 Clinical Trial.
Factors for severe outcomes following SARS-CoV-2 infection in people with cystic fibrosis in Europe.
Jung A, Orenti A, Dunlevy F, Aleksejeva E, Bakkeheim E, Bobrovnichy V, Carr SB, Colombo C, Corvol H, Cosgriff R, Daneau G, Dogru D, Drevinek P, Vukic AD, Fajac I, Fox A, Fustik S, Gulmans V, Harutyunyan S, Hatziagorou E, Kasmi I, Kayserová H, Kondratyeva E, Krivec U, Makukh H, Malakauskas K, McKone EF, Mei-Zahav M, de Monestrol I, Olesen HV, Padoan R, Parulava T, Pastor-Vivero MD, Pereira L, Petrova G, Pfleger A, Pop L, van Rens JG, Rodic M, Schlesser M, Storms V, Turcu O, Woz Niacki L, Yiallouros P, Zolin A, Downey DG, Naehrlich L. Jung A, et al. Among authors: downey dg. ERJ Open Res. 2021 Dec 27;7(4):00411-2021. doi: 10.1183/23120541.00411-2021. eCollection 2021 Oct. ERJ Open Res. 2021. PMID: 34984210 Free PMC article.
Neutrophils in cystic fibrosis.
Downey DG, Bell SC, Elborn JS. Downey DG, et al. Thorax. 2009 Jan;64(1):81-8. doi: 10.1136/thx.2007.082388. Thorax. 2009. PMID: 19103874 Review.
Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study.
Flume PA, Biner RF, Downey DG, Brown C, Jain M, Fischer R, De Boeck K, Sawicki GS, Chang P, Paz-Diaz H, Rubin JL, Yang Y, Hu X, Pasta DJ, Millar SJ, Campbell D, Wang X, Ahluwalia N, Owen CA, Wainwright CE; VX14-661-110 study group. Flume PA, et al. Among authors: downey dg. Lancet Respir Med. 2021 Jul;9(7):733-746. doi: 10.1016/S2213-2600(20)30510-5. Epub 2021 Feb 10. Lancet Respir Med. 2021. PMID: 33581080
Airway Inflammation and Host Responses in the Era of CFTR Modulators.
Keown K, Brown R, Doherty DF, Houston C, McKelvey MC, Creane S, Linden D, McAuley DF, Kidney JC, Weldon S, Downey DG, Taggart CC. Keown K, et al. Among authors: downey dg. Int J Mol Sci. 2020 Sep 2;21(17):6379. doi: 10.3390/ijms21176379. Int J Mol Sci. 2020. PMID: 32887484 Free PMC article. Review.
69 results