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Year Number of Results
1996 1
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2011 3
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182 results

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Page 1
DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer.
Matsunuma R, Chan DW, Kim BJ, Singh P, Han A, Saltzman AB, Cheng C, Lei JT, Wang J, Roberto da Silva L, Sahin E, Leng M, Fan C, Perou CM, Malovannaya A, Ellis MJ. Matsunuma R, et al. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11978-E11987. doi: 10.1073/pnas.1810598115. Epub 2018 Nov 29. Proc Natl Acad Sci U S A. 2018. PMID: 30498031 Free PMC article.
A PubMed informatics tool indicated a paucity of data in the context of breast cancer, which further prioritized DPYSL3 for study. DPYSL3 knockdown in DPYSL3-positive ([Formula: see text]) CLOW cell lines demonstrated reduced proliferation, yet enhanced motil …
A PubMed informatics tool indicated a paucity of data in the context of breast cancer, which further prioritized DPYSL3 for study. …
Upregulation of dihydropyrimidinase-like 3 (DPYSL3) protein predicts poor prognosis in urothelial carcinoma.
Liang PI, Lai HY, Chan TC, Li WM, Hsing CH, Huang SK, Hsieh KL, Tseng WH, Chen TJ, Li WS, Chen HD, Kuo YH, Li CF. Liang PI, et al. BMC Cancer. 2023 Jun 28;23(1):599. doi: 10.1186/s12885-023-11090-z. BMC Cancer. 2023. PMID: 37380971 Free PMC article.
Fresh tumour tissue from 50 patients was used to examine the DPYSL3 mRNA level. In addition, urothelial cell lines with and without DPYSL3 knockdown were used for the functional study. ...Therefore, DPYSL3 can be used as a novel therapeutic target for UC....
Fresh tumour tissue from 50 patients was used to examine the DPYSL3 mRNA level. In addition, urothelial cell lines with and without …
Inhibition of cell-adhesion protein DPYSL3 promotes metastasis of lung cancer.
Yang Y, Jiang Y, Xie D, Liu M, Song N, Zhu J, Fan J, Zhu C. Yang Y, et al. Respir Res. 2018 Mar 7;19(1):41. doi: 10.1186/s12931-018-0740-0. Respir Res. 2018. PMID: 29514686 Free PMC article.
Cell migration and invasion assays were performed to determine the role of DPYSL3 in LLC cells' migration and invasion changes. A metastatic lung tumor model in which the stable DPYSL3 knockdown LLC cells were injected through tail vein was used to analyze the role …
Cell migration and invasion assays were performed to determine the role of DPYSL3 in LLC cells' migration and invasion changes. A met …
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression.
Feng YH, Lim SW, Lin HY, Wang SA, Hsu SP, Kao TJ, Ko CY, Hsu TI. Feng YH, et al. J Steroid Biochem Mol Biol. 2022 May;219:106067. doi: 10.1016/j.jsbmb.2022.106067. Epub 2022 Jan 31. J Steroid Biochem Mol Biol. 2022. PMID: 35114375
Furthermore, quantitative proteomic analysis, iTRAQ, showed that allo significantly decreased the levels of DPYSL3, S100A11, and S100A4, reflecting the poor prognosis of patients with GBM confirmed by differential gene expression and survival analysis. Moreover, single-cel …
Furthermore, quantitative proteomic analysis, iTRAQ, showed that allo significantly decreased the levels of DPYSL3, S100A11, and S100 …
Suppression of Prostate Cancer Metastasis by DPYSL3-Targeted saRNA.
Li B, Li C. Li B, et al. Adv Exp Med Biol. 2017;983:207-216. doi: 10.1007/978-981-10-4310-9_15. Adv Exp Med Biol. 2017. PMID: 28639202
Metastasis is the sole cause of cancer death and there is no curable means in clinic. Cellular protein CRMP4 (DPYSL3 gene) was previously defined as a metastasis suppressor in human prostate cancers since its expression is dramatically reduced in lymphatic metastatic disea …
Metastasis is the sole cause of cancer death and there is no curable means in clinic. Cellular protein CRMP4 (DPYSL3 gene) was previo …
Enhancing DPYSL3 gene expression via a promoter-targeted small activating RNA approach suppresses cancer cell motility and metastasis.
Li C, Jiang W, Hu Q, Li LC, Dong L, Chen R, Zhang Y, Tang Y, Thrasher JB, Liu CB, Li B. Li C, et al. Oncotarget. 2016 Apr 19;7(16):22893-910. doi: 10.18632/oncotarget.8290. Oncotarget. 2016. PMID: 27014974 Free PMC article.
The target gene in this study is Dihydro-pyrimidinase-like 3 (DPYSL3, protein name CRMP4), which was identified as a metastatic suppressor in prostate cancers. There are two transcriptional variants of DPYSL3 gene in human genome, of which the variant 2 is the domin …
The target gene in this study is Dihydro-pyrimidinase-like 3 (DPYSL3, protein name CRMP4), which was identified as a metastatic suppr …
Dihydropyrimidinase-like 3 is a putative hepatocellular carcinoma tumor suppressor.
Oya H, Kanda M, Sugimoto H, Shimizu D, Takami H, Hibino S, Hashimoto R, Okamura Y, Yamada S, Fujii T, Nakayama G, Koike M, Nomoto S, Fujiwara M, Kodera Y. Oya H, et al. J Gastroenterol. 2015 May;50(5):590-600. doi: 10.1007/s00535-014-0993-4. Epub 2014 Aug 31. J Gastroenterol. 2015. PMID: 25173447
Further, we determined the methylation status of the DPYSL3 promoter in HCC cells lines and the effect of inhibiting DPYSL3 expression on their phenotype. DPYSL3 expression was determined in 151 pairs of resected liver tissues. RESULTS: DPYSL3 mRNA lev …
Further, we determined the methylation status of the DPYSL3 promoter in HCC cells lines and the effect of inhibiting DPYSL3 ex …
Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish.
Tanaka H, Morimura R, Ohshima T. Tanaka H, et al. Dev Biol. 2012 Oct 15;370(2):223-36. doi: 10.1016/j.ydbio.2012.07.032. Epub 2012 Aug 8. Dev Biol. 2012. PMID: 22898304 Free article.
Dpysl2 (CRMP2) and Dpysl3 (CRMP4) are involved in neuronal polarity and axon elongation in cultured neurons. ...These results suggest that the phosphorylation of Dpysl2 and Dpysl3 by Cdk5 and DYRK2 is required for the proper positioning of RB neurons and NCCs during …
Dpysl2 (CRMP2) and Dpysl3 (CRMP4) are involved in neuronal polarity and axon elongation in cultured neurons. ...These results suggest …
Calpain-mediated truncation of dihydropyrimidinase-like 3 protein (DPYSL3) in response to NMDA and H2O2 toxicity.
Kowara R, Chen Q, Milliken M, Chakravarthy B. Kowara R, et al. J Neurochem. 2005 Oct;95(2):466-74. doi: 10.1111/j.1471-4159.2005.03383.x. Epub 2005 Aug 31. J Neurochem. 2005. PMID: 16135096 Free article.
Analysis of the DPYSL3 protein sequence revealed a possible cleavage site for calpain (Val-Arg-Ser) on the C-terminus of DPYSL3. Collectively, these studies demonstrate for the first time that DPYSL3 is a calpain substrate. The physiological relevance of the …
Analysis of the DPYSL3 protein sequence revealed a possible cleavage site for calpain (Val-Arg-Ser) on the C-terminus of DPYSL3 …
182 results