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Page 1
The chemistry of nitroxyl-releasing compounds.
DuMond JF, King SB. DuMond JF, et al. Antioxid Redox Signal. 2011 May 1;14(9):1637-48. doi: 10.1089/ars.2010.3838. Epub 2011 Mar 2. Antioxid Redox Signal. 2011. PMID: 21235345 Free PMC article. Review.
Nitroxyl accelerates the oxidation of oxyhemoglobin by nitrite.
Bellavia L, DuMond JF, Perlegas A, Bruce King S, Kim-Shapiro DB. Bellavia L, et al. Among authors: dumond jf. Nitric Oxide. 2013 May 31;31:38-47. doi: 10.1016/j.niox.2013.03.006. Epub 2013 Mar 30. Nitric Oxide. 2013. PMID: 23545404 Free PMC article.
Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.
Cortese-Krott MM, Kuhnle GG, Dyson A, Fernandez BO, Grman M, DuMond JF, Barrow MP, McLeod G, Nakagawa H, Ondrias K, Nagy P, King SB, Saavedra JE, Keefer LK, Singer M, Kelm M, Butler AR, Feelisch M. Cortese-Krott MM, et al. Among authors: dumond jf. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4651-60. doi: 10.1073/pnas.1509277112. Epub 2015 Jul 29. Proc Natl Acad Sci U S A. 2015. PMID: 26224837 Free PMC article.
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