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Year Number of Results
1980 1
2008 1
2009 1
2014 2
2015 1
2016 1
2017 1
2018 2
2019 1
2020 3
2022 0
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11 results
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Page 1
Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.
Andryianau G, Kowalski M, Piotrowicz MC, Rajkiewicz AA, Dymek B, Sklepkiewicz PL, Pluta E, Stefaniak F, Czestkowski W, Olejniczak S, Mazur M, Niedziejko P, Koralewski R, Matyszewski K, Gruza M, Zagozdzon A, Salamon M, Rymaszewska A, Welzer M, Dzwonek K, Golab J, Olczak J, Bartoszewicz A, Golebiowski A. Andryianau G, et al. Among authors: dymek b. ACS Med Chem Lett. 2020 Apr 24;11(6):1228-1235. doi: 10.1021/acsmedchemlett.0c00092. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551005 Free PMC article.
Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.
Mazur M, Bartoszewicz A, Dymek B, Salamon M, Andryianau G, Kowalski M, Olejniczak S, Matyszewski K, Pluta E, Borek B, Stefaniak F, Zagozdzon A, Mazurkiewicz M, Koralewski R, Czestkowski W, Piotrowicz M, Niedziejko P, Gruza MM, Dzwonek K, Golebiowski A, Golab J, Olczak J. Mazur M, et al. Among authors: dymek b. Bioorg Med Chem Lett. 2018 Feb 1;28(3):310-314. doi: 10.1016/j.bmcl.2017.12.047. Epub 2017 Dec 22. Bioorg Med Chem Lett. 2018. PMID: 29292229
Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.
Mazur M, Dymek B, Koralewski R, Sklepkiewicz P, Olejniczak S, Mazurkiewicz M, Piotrowicz M, Salamon M, Jędrzejczak K, Zagozdzon A, Czestkowski W, Matyszewski K, Borek B, Bartoszewicz A, Pluta E, Rymaszewska A, Mozga W, Stefaniak F, Dobrzański P, Dzwonek K, Golab J, Golebiowski A, Olczak J. Mazur M, et al. Among authors: dymek b. J Med Chem. 2019 Aug 8;62(15):7126-7145. doi: 10.1021/acs.jmedchem.9b00681. Epub 2019 Jul 23. J Med Chem. 2019. PMID: 31291098
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Koralewski R, Dymek B, Mazur M, Sklepkiewicz P, Olejniczak S, Czestkowski W, Matyszewski K, Andryianau G, Niedziejko P, Kowalski M, Gruza M, Borek B, Jedrzejczak K, Bartoszewicz A, Pluta E, Rymaszewska A, Kania M, Rejczak T, Piasecka S, Mlacki M, Mazurkiewicz M, Piotrowicz M, Salamon M, Zagozdzon A, Napiorkowska-Gromadzka A, Bartlomiejczak A, Mozga W, Dobrzański P, Dzwonek K, Golab J, Nowotny M, Olczak J, Golebiowski A. Koralewski R, et al. Among authors: dymek b. J Med Chem. 2020 Dec 24;63(24):15527-15540. doi: 10.1021/acs.jmedchem.0c01179. Epub 2020 Oct 20. J Med Chem. 2020. PMID: 33078933
Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.
Mazur M, Olczak J, Olejniczak S, Koralewski R, Czestkowski W, Jedrzejczak A, Golab J, Dzwonek K, Dymek B, Sklepkiewicz PL, Zagozdzon A, Noonan T, Mahboubi K, Conway B, Sheeler R, Beckett P, Hungerford WM, Podjarny A, Mitschler A, Cousido-Siah A, Fadel F, Golebiowski A. Mazur M, et al. Among authors: dymek b. J Med Chem. 2018 Feb 8;61(3):695-710. doi: 10.1021/acs.jmedchem.7b01051. Epub 2018 Jan 11. J Med Chem. 2018. PMID: 29283260
Activating mutations in ALK kinase domain confer resistance to structurally unrelated ALK inhibitors in NPM-ALK-positive anaplastic large-cell lymphoma.
Zdzalik D, Dymek B, Grygielewicz P, Gunerka P, Bujak A, Lamparska-Przybysz M, Wieczorek M, Dzwonek K. Zdzalik D, et al. Among authors: dymek b. J Cancer Res Clin Oncol. 2014 Apr;140(4):589-98. doi: 10.1007/s00432-014-1589-3. Epub 2014 Feb 8. J Cancer Res Clin Oncol. 2014. PMID: 24509625 Free PMC article.
11 results