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Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials.
Hey-Hadavi J, Seekins D, Palmer M, Coffey D, Caminis J, Abdullaev S, Patwardhan M, Tyler H, Raheja R, Stanley AM, Pineda-Salgado L, Bourdet DL, Andrade RJ, Hayashi PH, Dimick-Santos L, Rockey DC, Estilo A. Hey-Hadavi J, et al. Drug Saf. 2021 Jun;44(6):619-634. doi: 10.1007/s40264-021-01051-5. Epub 2021 Mar 16. Drug Saf. 2021. PMID: 33725335 Free PMC article. Review.
Adjudication committees comprised of SMEs (i.e., utilizing expert opinion) remain the standard for DILI causality assessment. A variety of working groups continue to make progress in pursuing new tools to assist with DILI causality assessment. ...
Adjudication committees comprised of SMEs (i.e., utilizing expert opinion) remain the standard for DILI causality assessment. A varie …
High-resolution ion mobility spectrometry-mass spectrometry for isomeric separation of prostanoids after Girard's reagent T derivatization.
Lamont L, Hadavi D, Bowman AP, Flinders B, Cooper-Shepherd D, Palmer M, Jordens J, Mengerink Y, Honing M, Langridge J, Porta Siegel T, Vreeken RJ, Heeren RMA. Lamont L, et al. Rapid Commun Mass Spectrom. 2023 Mar 15;37(5):e9439. doi: 10.1002/rcm.9439. Rapid Commun Mass Spectrom. 2023. PMID: 36415963 Free PMC article.
Multiple prostanoid isomers have distinct in vivo functions crucial for understanding the inflammation process, including prostaglandins E(2) (PGE(2) ) and D(2) (PGD(2) ). High-resolution ion mobility spectrometry (IMS) based on linear ion transport in low-to-moderate elec …
Multiple prostanoid isomers have distinct in vivo functions crucial for understanding the inflammation process, including prostaglandins …
Cold Atmospheric Plasma Is a Potent Tool to Improve Chemotherapy in Melanoma In Vitro and In Vivo.
Alimohammadi M, Golpur M, Sohbatzadeh F, Hadavi S, Bekeschus S, Niaki HA, Valadan R, Rafiei A. Alimohammadi M, et al. Biomolecules. 2020 Jul 8;10(7):1011. doi: 10.3390/biom10071011. Biomolecules. 2020. PMID: 32650505 Free PMC article.
Assays on cell growth, apoptosis, and expression of genes related to, e.g., autophagic processes, showed CAP to have a substantial impact in melanoma cells while there were only minoreffects in L929 cells. ...
Assays on cell growth, apoptosis, and expression of genes related to, e.g., autophagic processes, showed CAP to have a substantial im …
Effect of different adhesive systems on microleakage at the amalgam/composite resin interface.
Hadavi F, Hey JH, Ambrose ER, Elbadrawy HE. Hadavi F, et al. Oper Dent. 1993 Jan-Feb;18(1):2-7. Oper Dent. 1993. PMID: 8332537
The results indicated that the application of Prisma Universal Bond 2 adhesive, Cover Up II, or Amalgambond (groups E, F, and G) reduced the amount of microleakage significantly as compared to the groups in which no adhesive system, 3M Porcelain Repair Kit (with and withou …
The results indicated that the application of Prisma Universal Bond 2 adhesive, Cover Up II, or Amalgambond (groups E, F, and G) redu …
Autosomal recessive mental retardation: homozygosity mapping identifies 27 single linkage intervals, at least 14 novel loci and several mutation hotspots.
Kuss AW, Garshasbi M, Kahrizi K, Tzschach A, Behjati F, Darvish H, Abbasi-Moheb L, Puettmann L, Zecha A, Weissmann R, Hu H, Mohseni M, Abedini SS, Rajab A, Hertzberg C, Wieczorek D, Ullmann R, Ghasemi-Firouzabadi S, Banihashemi S, Arzhangi S, Hadavi V, Bahrami-Monajemi G, Kasiri M, Falah M, Nikuei P, Dehghan A, Sobhani M, Jamali P, Ropers HH, Najmabadi H. Kuss AW, et al. Hum Genet. 2011 Feb;129(2):141-8. doi: 10.1007/s00439-010-0907-3. Epub 2010 Nov 10. Hum Genet. 2011. PMID: 21063731
Altogether, 13 out of 39 single linkage intervals observed in our cohort were found to cluster at 6 different loci on chromosomes, i.e., 1p34, 4q27, 5p15, 9q34, 11p11-q13 and 19q13, respectively. Five of these clusters consist of two significantly overlapping linkage inter …
Altogether, 13 out of 39 single linkage intervals observed in our cohort were found to cluster at 6 different loci on chromosomes, i.e