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99 results

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Page 1
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Abskharon R, et al. Among authors: eisenberg ds. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2300258120. doi: 10.1073/pnas.2300258120. Epub 2023 Oct 6. Proc Natl Acad Sci U S A. 2023. PMID: 37801475 Free PMC article.
Toward the Atomic Structure of PrPSc.
Rodriguez JA, Jiang L, Eisenberg DS. Rodriguez JA, et al. Among authors: eisenberg ds. Cold Spring Harb Perspect Biol. 2017 Sep 1;9(9):a031336. doi: 10.1101/cshperspect.a031336. Cold Spring Harb Perspect Biol. 2017. PMID: 28096267 Free PMC article. Review.
Taking the measure of MicroED.
Rodriguez JA, Eisenberg DS, Gonen T. Rodriguez JA, et al. Among authors: eisenberg ds. Curr Opin Struct Biol. 2017 Oct;46:79-86. doi: 10.1016/j.sbi.2017.06.004. Epub 2017 Jun 22. Curr Opin Struct Biol. 2017. PMID: 28648726 Free PMC article. Review.
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L. Nguyen BA, et al. Among authors: eisenberg ds. Nat Commun. 2024 Jan 17;15(1):581. doi: 10.1038/s41467-024-44820-3. Nat Commun. 2024. PMID: 38233397 Free PMC article.
Propagation of Tau Aggregates and Neurodegeneration.
Goedert M, Eisenberg DS, Crowther RA. Goedert M, et al. Among authors: eisenberg ds. Annu Rev Neurosci. 2017 Jul 25;40:189-210. doi: 10.1146/annurev-neuro-072116-031153. Annu Rev Neurosci. 2017. PMID: 28772101 Review.
D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease.
Hou K, Pan H, Shahpasand-Kroner H, Hu C, Abskharon R, Seidler P, Mekkittikul M, Balbirnie M, Lantz C, Sawaya MR, Dolinsky JL, Jones M, Zuo X, Loo JA, Frautschy S, Cole G, Eisenberg DS. Hou K, et al. Among authors: eisenberg ds. Sci Adv. 2024 May 3;10(18):eadl2991. doi: 10.1126/sciadv.adl2991. Epub 2024 May 1. Sci Adv. 2024. PMID: 38691615 Free PMC article.
99 results