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2017 3
2020 3
2021 3
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Page 1
CaM Kinase II-δ Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy.
Chen J, Fleming T, Katz S, Dewenter M, Hofmann K, Saadatmand A, Kronlage M, Werner MP, Pokrandt B, Schreiter F, Lin J, Katz D, Morgenstern J, Elwakiel A, Sinn P, Gröne HJ, Hammes HP, Nawroth PP, Isermann B, Sticht C, Brügger B, Katus HA, Hagenmueller M, Backs J. Chen J, et al. Among authors: elwakiel a. Diabetes. 2021 Feb;70(2):616-626. doi: 10.2337/db19-0659. Epub 2020 Nov 25. Diabetes. 2021. PMID: 33239449
Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently.
Gadi I, Fatima S, Elwakiel A, Nazir S, Mohanad Al-Dabet M, Rana R, Bock F, Manoharan J, Gupta D, Biemann R, Nieswandt B, Braun-Dullaeus R, Besler C, Scholz M, Geffers R, Griffin JH, Esmon CT, Kohli S, Isermann B, Shahzad K. Gadi I, et al. Among authors: elwakiel a. Circ Res. 2021 Feb 19;128(4):513-529. doi: 10.1161/CIRCRESAHA.120.317219. Epub 2020 Dec 23. Circ Res. 2021. PMID: 33353373
Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition.
Nazir S, Gadi I, Al-Dabet MM, Elwakiel A, Kohli S, Ghosh S, Manoharan J, Ranjan S, Bock F, Braun-Dullaeus RC, Esmon CT, Huber TB, Camerer E, Dockendorff C, Griffin JH, Isermann B, Shahzad K. Nazir S, et al. Among authors: elwakiel a. Blood. 2017 Dec 14;130(24):2664-2677. doi: 10.1182/blood-2017-05-782102. Epub 2017 Sep 7. Blood. 2017. PMID: 28882883 Free PMC article.
Podocyte Integrin-β 3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.
Madhusudhan T, Ghosh S, Wang H, Dong W, Gupta D, Elwakiel A, Stoyanov S, Al-Dabet MM, Krishnan S, Biemann R, Nazir S, Zimmermann S, Mathew A, Gadi I, Rana R, Zeng-Brouwers J, Moeller MJ, Schaefer L, Esmon CT, Kohli S, Reiser J, Rezaie AR, Ruf W, Isermann B. Madhusudhan T, et al. Among authors: elwakiel a. J Am Soc Nephrol. 2020 Aug;31(8):1762-1780. doi: 10.1681/ASN.2019111163. Epub 2020 Jul 24. J Am Soc Nephrol. 2020. PMID: 32709711
Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.
Madhusudhan T, Wang H, Ghosh S, Dong W, Kumar V, Al-Dabet MM, Manoharan J, Nazir S, Elwakiel A, Bock F, Kohli S, Marquardt A, Sögüt I, Shahzad K, Müller AJ, Esmon CT, Nawroth PP, Reiser J, Chavakis T, Ruf W, Isermann B. Madhusudhan T, et al. Among authors: elwakiel a. Blood. 2017 Sep 21;130(12):1445-1455. doi: 10.1182/blood-2017-02-767921. Epub 2017 Jul 7. Blood. 2017. PMID: 28687614 Free PMC article.
Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy.
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B. Marquardt A, et al. Among authors: elwakiel a. J Am Soc Nephrol. 2017 Nov;28(11):3182-3189. doi: 10.1681/ASN.2016101123. Epub 2017 Jul 10. J Am Soc Nephrol. 2017. PMID: 28696246 Free PMC article.