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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2001 2
2003 2
2004 1
2006 1
2007 1
2008 2
2010 2
2011 4
2012 2
2013 2
2015 4
2016 2
2017 1
2018 1
2019 1
2022 1
2023 1

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28 results

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Page 1
The use of bioreactors as in vitro models in pharmaceutical research.
Ginai M, Elsby R, Hewitt CJ, Surry D, Fenner K, Coopman K. Ginai M, et al. Among authors: elsby r. Drug Discov Today. 2013 Oct;18(19-20):922-35. doi: 10.1016/j.drudis.2013.05.016. Epub 2013 Jun 5. Drug Discov Today. 2013. PMID: 23748137 Review.
Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.
Chu X, Korzekwa K, Elsby R, Fenner K, Galetin A, Lai Y, Matsson P, Moss A, Nagar S, Rosania GR, Bai JP, Polli JW, Sugiyama Y, Brouwer KL; International Transporter Consortium. Chu X, et al. Among authors: elsby r. Clin Pharmacol Ther. 2013 Jul;94(1):126-41. doi: 10.1038/clpt.2013.78. Epub 2013 Apr 10. Clin Pharmacol Ther. 2013. PMID: 23588320 Free PMC article. Review.
Mechanistic in vitro studies indicate that the clinical drug-drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3.
Elsby R, Coghlan H, Edgerton J, Hodgson D, Outteridge S, Atkinson H. Elsby R, et al. Pharmacol Res Perspect. 2023 Apr;11(2):e01060. doi: 10.1002/prp2.1060. Pharmacol Res Perspect. 2023. PMID: 36811234 Free PMC article.
NFAR-1 and -2 modulate translation and are required for efficient host defense.
Pfeifer I, Elsby R, Fernandez M, Faria PA, Nussenzveig DR, Lossos IS, Fontoura BM, Martin WD, Barber GN. Pfeifer I, et al. Among authors: elsby r. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4173-8. doi: 10.1073/pnas.0711222105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337511 Free PMC article.
Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine.
Elsby R, Chidlaw S, Outteridge S, Pickering S, Radcliffe A, Sullivan R, Jones H, Butler P. Elsby R, et al. Pharmacol Res Perspect. 2017 Oct;5(5):e00357. doi: 10.1002/prp2.357. Pharmacol Res Perspect. 2017. PMID: 28971610 Free PMC article.
28 results